Asthma and Allergy

Asthma is the most prevalent chronic respiratory disease in children and is also very common in adults. Although the clinical manifestations of asthma in children and adults are rather uniform (e.g. wheezing, shortness of breath, and cough), population-based clinical and genetic studies suggest that asthma is not one but many diseases. Thus, a single “one-size-fits-all” treatment approach is unlikely to work to tackle this important health problem. In order to design personalized treatment approaches for asthma patients, there is urgent need to elucidate the particular molecular mechanisms underlying the various types of asthma. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma and Allergy of the DZL.

Scientific Coordinators of the Disease Area

Prof. Dr. Susanne Krauss-Etschmann (ARCN)
Prof. Dr. Erika von Mutius (CPC-M)

Administrativer Coordinator of the Disease Area

Dr. Jörn Bullwinkel (ARCN)

Participating DZL Partner Sites


All Age Asthma Cohort (ALLIANCE)

The ALLIANCE cohort now comprises more than 1,000 patients and healthy subjects aged between six months and 84 years.

News about Asthma and Allergies

13. October 2021

Childhood asthma is evident in the blood

Specific immune cells are less abundant in children with allergic asthma than in healthy individuals.
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24. August 2021

Will an individual asthma therapy succeed? – Lung collagen degradation might tell

Researchers of DZL analyzed lung collagen degradation and found a way to predict the course of an antibody therapy with omalizumab.
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11. August 2021

Model to serve as basis for new therapeutic strategies

COVID-19 disease severity is determined by the individual patient’s immune response. The precise mechanisms taking place inside the lungs and blood during the early phase of the disease remain unclear.
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All Asthma and Allergy news