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Coordinator(s)/ scientist(s) |
Disease Area |
DZL Partner Site(s) involved |
Title |
| Behr J / Günther A | Diffuse Parenchymal Lung Disease (DPLD) | all | Exploratory efficacy and safety study of oral pirfenidone for progressive, non-IPF lung fibrosis (RELIEF in lung fibrosis) |
| Griese M | Diffuse Parenchymal Lung Disease (DPLD) | all | Hydroxychloroquine (HCQ) in pediatric ILD (= children‘s interstitial lung disease; chILD) |
| Herold S | Pneumonia and Acute Lung Injury | BREATH, UGMLC | GM-CSF Inhalation to improve HOst defense and Pulmonary barrier rEsoration (GI-HOPE) |
| Herold S / Lohmeyer J / Welte T | Pneumonia and Acute Lung Injury | BREATH, UGMLC | Promotion of host defense and alveolar barrier regeneration by inhaled GM-CSF in patients with pneumonia-associated ARDS |
| Heußel C | Lung Cancer | BREATH, CPC-M, TLRC, UGMLC | Early response capturing in the treatment of adenocarcinoma |
| Jobst B | COPD | all | Imaging disease progression in COP |
| Kreuter M / Vogelmeier C / Herth F | COPD | TLRC, UGMLC | Exploring efficacy of peridontal treatment on systemic inflammation and for prevention of exacerbations in patients with COPD: A multi-center, prospective, randomized, controlled, parallel-group pilot study |
| Reck M / Ammerpohl O / Barreto G | Lung Cancer | all | Monitoring of patients with NLCLC – epigenetic analysis of liquid biopsies and RNA-analysis in exhaled breath condensates |
| Schulz H / Meiners S / Vogelmeier C / Behr J | COPD | CPC-M, UGMLC | Proteasom Function as a Bio-Marker for COPD |
| Seeger W / Ghofrani A / Gall H | Pulmonary Hypertension | BREATH, UGMLC | Influence of specific PAH medication on right ventricular function in patients with pulmonary arterial hypertension |
| Tümmler B | Cystic Fibrosis / Mucoviscidosis | BREATH, TLRC, UGMLC | Orkambifacts – Intestinal current measurements (ICM) to evaluate the activation of mutant CFTR in treated with lumacaftor in combination with ivacaftor. |
| Vogel-Claussen J | Radiology / Pulmonale Hypertronie | BREATH, CPC-M, UGMLC, TLRC | Change-MRI – Phase III diagnostic trial to demonstrate that functional lung MRI can replace VQ-SPECT in a diagnostic strategy for patients with suspected CTEPH. |
| Vogelmeier C | COPD | ARCN, BREATH, UGMLC | Clinical study to investigate safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of multiple doses of the human GATA-3-specific DNAzyme solution SB010 in patients with moderate to severe COPD – A randomised, double-blind, parallel, multicentre, phase IIa pilot study |
| Zabel P / Herth F / König I / Rabe K / Welte T | COPD | ARCN, BREATH, TLRC | Evaluation of non-invasive pursed-lip breathing ventilation in advanced COPD |
