The structure of DZL

Supported Investigator Initiated Trials

Coordinator(s)/ scientist(s)
Disease Area
DZL Partner Site(s) involved
S. Herold / T. Welte Acute Lung Injury UGMLC, BREATH GI HOPE: Promotion of host defense and alveolar barrier regeneration by inhaled GM-CSF in patients with pneumonia-associated ARDS
M. Kreuter / C. Vogelmeier / F. Herth COPD UGMLC, TLRC ExperTENTION: Exploring efficacy of peridontal treatment on systemic inflammation and for prevention of exacerbations in patients with COPD: A multi-center, prospective, randomized, controlled, parallel-group pilot study
M. Reck / O. Ammerpohl Lung Cancer UGMLC EMO-Lung: Monitoring of patients with NLCLC – epigenetic analysis of liquid biopsies and RNA-analysis in exhaled breath condensates
H. Schulz / S. Meiners / J. Behr / C. Vogelmeier COPD CPC-M, UGMLC PBMC: Proteasom Function as a Bio-Marker for COPD
W. Seeger / A. Ghofrani Pulmonary Hypertension UGMLC Right Heart 3: Influence of specific PAH medication on right ventricular function in patients with pulmonary arterial hypertension
J. Vogel-Claussen Pulmonary Hypertension / Platform Imaging BREATH Change MRI: Phase III diagnostic trial to demonstrate that functional lung MRI can replace VQ-SPECT in a diagnostic strategy for patients with suspected CTEPH.
P. Zabel / F. Herth COPD ARCN, TLRC PLBV: Evaluation of non-invasive pursed-lip breathing ventilation in advanced COPD
O. Sommerburg Cystic Fibrosis TLRC ANAKIN: Study to evaluate the safety and efficacy of subcutaneous Administration of Anakinra in patients with cystic fibrosis
M. Eichhorn / R. Savai Lung Cancer TLRC, UGMLC Neomun Trial: Neoadjuvant anti PD-1 immunotherapy in resectable NSCLC.
J. Behr / P. Mertsch / F. Ringshausen / J. Rademacher Bronchiectasis Disease CPC-M, BREATH Eradicate: Inhaled Levofloxacin in adult bronchiectasis patients with early asymptomatic Pseudomonas aeruginosa infection
N. Kneidinger/ A.Ö. Yildirim / M. Hecker End-Stage Lung Disease CPC-M, UGMLC CatBOS: Cathepsin-B (CatB) as a new biomarker and therapeutic target for early bronchiolotis obliterans syndrome (BOS) after lung transplantation
J. Vogel-Claussen / S. Bohnet / M. Reck Lung Cancer BREATH, ARCN HANSE Study: Holistic implementation study Assessing a Northern German interdisciplinary lung cancer screening effort
S. Herold / T. Welte Acute Lung Injury UGMLC, BREATH Cyclosporine A: Early intervention treatment of SARS-CoV-2 with liposomal Cyclosporine A for Inhalation (L-CsA-i) in non-hospitalized patients due to Covid 19

DZL Engagements