Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD) is characterized by a progressive and largely irreversible restriction of lung function. Shortness of breath, the most often observed symptom of COPD, contributes significantly to the decrease in the quality of life of many patients. Although COPD can, to a certain extent, be avoided, the disease is the fourth most frequent cause of death worldwide. The main causes of this disease are smoking and air pollution.

COPD combined with an emphysema is the most frequently occurring destructive lung disease. The loss of structural integrity and the lung’s ability to regenerate are critical factors for the course of the disease and therapeutic success; the basic mechanisms are, however, hitherto hardly known. The long-term aim of the DZL research in this area is to translate new therapy concepts based on mechanisms into effective treatment for COPD patients.

Scientific Coordinators of the Disease Area

Prof. Dr. Klaus F. Rabe (ARCN)
Prof. Dr. Claus F. Vogelmeier (UGMLC)

Administrativer Coordinator of the Disease Area

Dr. Jörn Bullwinkel (ARCN)

Participating DZL Partner Sites


News about Chronic Obstructive Pulmonary Disease (COPD)

10. June 2020

Drug Against COPD in Sight

Work group of DZL researcher identifies target molecule for the treatment of chronic obstructive pulmonary disease (COPD).
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21. March 2019

The Lung Microbiome – the latest ERS Monograph

Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis.
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7. January 2019

COPD and Its Comorbidities: New Evidence Gained from the COSYCONET Cohort Study

The cohort study COSYCONET investigates how lung health, comorbidities, and systemic inflammation are related in patients with Chronic Obstructive Pulmonary Disease (COPD).
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All COPD news