Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD) is characterized by a progressive and largely irreversible restriction of lung function. Shortness of breath, the most often observed symptom of COPD, contributes significantly to the decrease in the quality of life of many patients. Although COPD can, to a certain extent, be avoided, the disease is the fourth most frequent cause of death worldwide. The main causes of this disease are smoking and air pollution.

COPD combined with an emphysema is the most frequently occurring destructive lung disease. The loss of structural integrity and the lung’s ability to regenerate are critical factors for the course of the disease and therapeutic success; the basic mechanisms are, however, hitherto hardly known. The long-term aim of the DZL research in this area is to translate new therapy concepts based on mechanisms into effective treatment for COPD patients.

Scientific Coordinators of the Disease Area

Prof. Dr. Klaus F. Rabe (ARCN)
Prof. Dr. Claus F. Vogelmeier (UGMLC)

Administrativer Coordinator of the Disease Area

Dr. Jörn Bullwinkel (ARCN)

Participating DZL Partner Sites


News about Chronic Obstructive Pulmonary Disease (COPD)

7. July 2021

DZL scientists fills important gap in lung research

Researchers from the DZL's BREATH site in Hanover are the first to clearly demonstrate the existence of lipofibroblasts in the human lung using electron microscopy.
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5. November 2020

Promising Therapeutic Approach against COPD

DZL-Researchers have now succeeded in curing COPD in mice. Their goal is to test the novel therapeutic approach in human clinical trials over the next few years.
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22. September 2020

Borstel scientists awarded with Innovation Transfer Prize 2020 of Werner Petersen Foundation

Dr. Stephan Rüller, Susanne Greve, Dr. Christian Herzmann and FLO-Medizintechnik were awarded with the Innovation Transfer Prize 2020 of the Werner Petersen Foundation.
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All COPD news