Coordinators: Sébastien Boutin und Burkhard Tümmler
The main focus of this working group is to provide a state-of-the-art microbiome/metagenome analytic pipeline with adequate bioinformatic and AI expertise for all DZL sites. This will allow us to study microbiome evolution and lung “dysbiosis” (altered microbiome composition) not only in various chronic lung diseases, such as CF, non-CF bronchiectasis, COPD, BPD, asthma, lung fibrosis and end-stage lung disease but also in the context of acute COVID-19 infection and post-COVID-19 symptoms. Findings will be linked to disease-driving pathogenic sequelae and exploited for novel intervention strategies.
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