DZL Core Dataset

Science and Research

The DZL core data set represents the most important lung research parameters. All parameters that are part of at least two disease area core datasets were included.

Kategorie	Parameter	Value Set	Description
Biometric Data	Gender	Female Male Divers
Biometric Data	Age at visit
Biometric Data	Height
Biometric Data	Weight
Biometric Data	BMI
Diagnosis	Principle / leading / inclusion diagnosis	Lung Disease Healthy Control	In case of a lung disease, the date of the initial diagnosis is required.
Diagnosis	Lung comorbidities	Acute Respiratory Distress Syndrome (ARDS) Allergy Asthma Bronchiale Benign lesions Bronchopulmonary Dysplasia (BPD) Chronic Resp. Infections excl. TB Chronic obstructive pulmonary disease Cystic Fibrosis (CF) Diffuse parenchymal lung disease (DPLD) Obstructive sleep apnea Pleural Diseases Pneumonia Pulmonary Embolism Pulmonary Hypertension (PH) Regeneration and Organ Replacement Thoracic Cancer Tuberculosis (TB)	For each diagnostic group, an explicit 'yes', 'no' or 'asked but unknown' must be recorded. For each diagnostic group, the date of the initial diagnosis is required
Diagnosis	Non-lung comorbidities	Diabetes Arterial Hypertension Coronary Heart Disease Chronic Virus Infection Chronic Mycobacteriosis Hospital-associated Infection Tumor Neurological Disease	The given list of comorbidities covers the requirements of the DZG (german centers for health research) core dataset. It will soon be extended by the list of the most important comorbidities for the field of lung research. For each diagnostic group, an explicit 'yes', 'no' or 'asked but unknown' must be recorded. For each diagnostic group, the date of the initial diagnosis is required.
Health Questionnaires	MRC	MRC Grade 1 MRC Grade 2 MRC Grade 3 MRC Grade 4 MRC Grade 5	Medical Research Council (MRC) breathlessnes scale
Smoking History	Smoking Status	Active Smoker Ex Smoker Passive Smoker Never Smoker
Smoking History	Smoking Amount	Packyears Cigarettes per Day
Lung Function	FVC observed value		Forced Vital Capacity: the volume of air that can forcibly be blown out after full inspiration
Lung Function	FEV1 observed value		Forced Expiratory Volume in 1 second: the volume of air that has been exhaled at the end of the first second of forced expiration
Lung Function	TLC observed value		Total Lung Capacity: the volume of air in the lungs at maximum inflation
Lung Function	TLC%pred		Total Lung Capacity as percentage of the predicted value
Lung Function	RV observed value		Residual Volume: the amount of air remaining in the lungs after maximum exhalation
Lung Function	VC observed value		Vital Capacity: the largest volume a patient can exhale after a full inhalation
Lung Function	DLCO		Diffusion Capacity: the carbon monoxide uptake from a single inspiration in a standard time (usually 10 sec)
Lung Function	sRaw effektiv		Specific Airway Resistance
Blood Gas Analysis	Capillary pCO2		Partial pressure of carbon dioxide in capillary blood
Blood Gas Analysis	Capillary pO2		Partial pressure of oxygen in capillary blood
Exercise Testing	6MWT distance		6 Minute Walkt Test: the distance walked in 6 minutes
Therapy	Supplemental oxygen therapy
Follow-UP	Lost to follow up
Follow-UP	Patient deceased	Patient deceased Date of death
Performance and Activity	EQ-5D-5L Mobility Score	1 - I have no problems in walking about 2 - I have slight problems in walking about 3 - I have moderate problems in walking about 4 - I have severe problems in walking about 5 - I am unable to walk about	The mobility dimension of the EQ-5D-5L system introduced by the EuroQol Group. There are similarities to other performance measurements like ECOG, Karnofsky and the WHO performance scale.
Biobank Samples	Blood Sample		The availability of blood samples for a certain patient

Overview: Core Datasets

DZL Core Dataset
Acute Lung Injury
Asthma and Allergy
Chronic Obstructive Pulmonary Disease (COPD)
Cystic Fibrosis (CF)
Diffuse Parenchymal Lung Disease (DPLD)
Lung Cancer
Lung Transplant (LTx)
Pneumonia
Pulmonary Hypertension (PH)

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