Science and Research

Health Care Situation in the Treatment of Uncontrolled GINA Step 4/5 Patients in Germany

PURPOSE: It has been estimated that, in 2019, 54,000 patients in Germany had uncontrolled GINA step 4/5 asthma. In the current study we analyzed which health care providers were involved in the management of these patients and their role in disease phenotyping. PATIENTS AND METHODS: The year 2019 was retrospectively analyzed using the IQVIA(TM) LRx, a longitudinal anonymized prescription database, and the electronic, anonymized medical records database, the IQVIA Disease Analyzer. RESULTS: Of 54,000 uncontrolled GINA step 4/5 asthma patients in Germany, 52% had consulted both general practitioners (GPs) and pulmonologists, and 48% were seen exclusively by a GP. Of these 54,000 patients, 45% were being prescribed and were thus overusing short-acting β2-agonists (SABAs) and oral corticosteroids (OCS) for ≥2 years, 26% for ≥3 years, and 16% for ≥4 years. In most regions, pulmonologists saw one of their uncontrolled GINA step 4/5 asthma patients per week. Laboratory tests from consultations with a GP were available for only 10% of patients referred to a pulmonologist. In 50% of uncontrolled asthma patients treated according to GINA step 4/5, these were initiated by the pulmonologist, and 34% received laboratory testing within the first year (in GINA step 4/5 asthma, the numbers are 20% and 18%, respectively). CONCLUSION: Fifty percent of uncontrolled asthma patients treated according to GINA step 4/5 were regularly seen by pulmonologists, who performed most of the phenotyping confirming their importance in the management of severe, uncontrolled asthma in Germany. To understand treatment pathways for these patients, further studies are needed.

  • Timmermann, H.
  • Milger, K.
  • Virchow, J. C.
  • Schmidt, O.
  • Bergmann, K. C.
  • Koschel, D.
  • Neurohr, C.
  • Scholz, F.
  • Heck, S.
  • Skowasch, D.

Keywords

  • Germany
  • biological treatment
  • laboratory test
  • prescription database
  • uncontrolled GINA step 4/5 asthma
Publication details
DOI: 10.2147/jaa.S418658
Journal: J Asthma Allergy
Pages: 813-820 
Work Type: Original
Location: CPC-M
Disease Area: AA
Partner / Member: KUM
Access-Number: 37559894

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