Pulmonary Hypertension (PH) - Deutsches Zentrum für Lungenforschung

Science and Research

The Pulmonary Hypertension (PH) core dataset represents the most important lung research parameters for the disease area.

Kategorie	Parameter	Value Set	Description
Biometric Data	Age at visit
Biometric Data	Gender	Diverse Female Male
Biometric Data	Race/Ethnic group finding	Black (Black African, Caribbean, British, any other black background) Other/Mixed Race (Mixed background, any other ethnic group) Caucasian/White (British, Irish, any other white background) Asian (Indian, Pakistani, Bangladeshi, Chinese, any other Asian background) Hispanic
Follow-UP	Date of death
Follow-UP	Lung transplantation
Follow-UP	Survival Status	Lost to follow up Deceased
Diagnosis	WHO Functional Class I II ( NYHA Classification I-IV)	NYHA I NYHA II NYHA III NYHA IV
Right heart catheteterization (RHC)	mPAP		Mean Pulmonary Arterial Pressure
Right heart catheteterization (RHC)	dPAP		Diastolic Pulmonary Artery Pressure
Right heart catheteterization (RHC)	PAWP		Pulmonary Arterial Wedge Pressure provides an indirect estimate of left atrial pressure.
Right heart catheteterization (RHC)	CVP / RAP		Central Venous Pressure is the blood pressure in teh vena cavae, near the right atrium of the heart.
Right heart catheteterization (RHC)	PVR		Pulmonary Vascular Resistance is the resistance against blood flow from the pulmonary artery to the left atrium.
Right heart catheteterization (RHC)	Cardiac Index by Fick		Hemodynamic parameter that relates the cardiac output (CO) from left ventricle in one minute to body surface area (BSA)
Right heart catheteterization (RHC)	Cardiac Index by Indicator dilution		Hemodynamic parameter that relates the cardiac output (CO) from left ventricle in one minute to body surface area (BSA)
Exercise Testing	6 Minute Walk Test Distance walked
Biobank Samples	Blood Sample		The availability of blood samples for a certain patient.
Lung Function	FEV1		Forced Expiratory Volume in 1 second: the volume of air that has been exhaled at the end of the first second of forced expiration
Lung Function	FEV1%pred		Forced Expiratory Volume in 1 second as percentage of the predicted value
Lung Function	FVC		Forced Vital Capacity: the volume of air that can forcibly be blown out after full inspiration
Lung Function	FVC%pred		Forced Vital Capacity as percentage of the predicted value
Lung Function	TLC%pred		Total Lung Capacity as percentage of the predicted value
Lung Function	DLCO%pred		CO uptake as percentage of the predicted value
Therapy	PH Specific Drug Therapy	Riociguat Treprostinil Sildenafil Imatinib Amlodipine Selexipag Epoprostenol Tadalafil Felodipine Vardenafil Verapamil Isradipine Lercanidipine Bosentan Nifedipine Sitaxentan Iloprost iv. Diltiazem

Overview: Core Datasets

DZL Core Dataset
Acute Lung Injury
Asthma and Allergy
Chronic Obstructive Pulmonary Disease (COPD)
Cystic Fibrosis (CF)
Diffuse Parenchymal Lung Disease (DPLD)
Lung Cancer (LC)
Lung Transplant (LTx)
Pneumonia
Pulmonary Hypertension (PH)

Contact

Authors
Prof. Henning Gall, UGMLC
Central Data Management