Asthma and Allergy - Deutsches Zentrum für Lungenforschung

Science and Research

The Asthma and Allergy core dataset represents the most important lung research parameters for the disease area.

Kategorie	Parameter	Value Set	Description
Biometric Data	Age at visit
Biometric Data	Weight
Biometric Data	Height
Biometric Data	BMI
Biometric Data	Prematurity (born < 37 + 0 week of pregnancy)
Smoking History	Smoking Status	Ex Smoker Passive Smoker Active Smoker Never Smoker
Smoking History	Amount	Packyears Zigaretten/Tag
Diagnosis	Healthy Control
Diagnosis	Asthma	Adult Asthma (> = 18 years) Childhood asthma (6-18years) Preschool wheeze (< 6 years only)
Diagnosis	Asthma severity	Moderate Mild Severe
Diagnosis	Allergy	Atopy Allergy: Doctors diagnosed allergic rhinoconjunctivitis Allergy: Doctors diagnose atopic eczema Allergy: Doctors diagnosed food allergy
Lung Function	Bronchial dilatation performed?		Bronchodilation refers to the effect of lung inflation after the induction of airway smooth muscle tone.
Lung Function	sRaw effective		Specific Airway Resistance
Lung Function	ITGV		Thoracic gas volume; absolute thorakal vol. of gas at any point in time and any level of alveolar pres.
Lung Function	ERV		Expiratory reserve volume; amount of air that can be breathed out after a normal exhalation.
Lung Function	IVC		Maximum amount of air a person can expel from the lungs after a maximum inhalation.
Lung Function	IVC - pre bronchodilatation
Lung Function	IVC - post bronchodilatation
Lung Function	TLC		TLC is the volume of air at maximum inflation.
Lung Function	TLC - pre bronchodilatation
Lung Function	TLC - post bronchodilatation
Lung Function	RV		RV is the amount of air remaining in the lungs after maximum exhalation.
Lung Function	RV - pre bronchodilatation
Lung Function	RV - post bronchodilatation
Lung Function	IC		IC is the volume of air that can be inspired after normal expiration.
Lung Function	DLCO		DLCO is the CO uptake from a single inspiration in a standard time.
Lung Function	DLCO/VA		Krogh factor (KCO) represents the diffusing capacity in the available alveolar spaces.
Lung Function	DLCO/VA - pre bronchodilatation
Lung Function	DLCO/VA - post bronchodilatation
Lung Function	DLCO Hb adj		ATS recommends for the adjustment of DLCO for Hb the equations from Cotes et al.
Lung Function	FEV1		FEV1 is the volume of air exhaled at the end of the first second of forced expiration.
Lung Function	FEV1 - pre bronchodilatation
Lung Function	FEV1 - post bronchodilatation
Lung Function	FVC		FVC is the volume of air that can forcibly be blown out after a full inspiration.
Lung Function	FVC - pre bronchodilatation
Lung Function	FVC - post bronchodilatation
Lung Function	Tiffeneau		A calculated ratio used in the diagnosis of obstructive and restrictive lung disease.
Lung Function	Tiffeneau - post bronchodilatation
Lung Function	FeNO		FeNO tests measure the level of airway inflammation in patient's lungs.

Overview: Core Datasets

DZL Core Dataset
Acute Lung Injury
Asthma and Allergy
Chronic Obstructive Pulmonary Disease (COPD)
Cystic Fibrosis (CF)
Diffuse Parenchymal Lung Disease (DPLD)
Lung Cancer (LC)
Lung Transplant (LTx)
Pneumonia
Pulmonary Hypertension (PH)

Contact

Authors
Dr. Nicole Maison, CPCM
Dr. Ruth Grychtol, BREATH
Central Data Management