- Das DZL
- Forschung
- DZL Academy
- Aktuelles
- Service
The Cystic Fibrosis (CF) core dataset represents the most important lung research parameters for the disease area.
| Kategorie | Parameter | Value Set | Description |
|---|---|---|---|
| Biometric Data | Gender | ||
| Biometric Data | Age at visit | ||
| Biometric Data | Weight | ||
| Biometric Data | Height | ||
| Biometric Data | BMI | ||
| Smoking History | Smoking Status | ||
| Smoking History | Amount | ||
| Diagnosis | Cystic Fibrosis (CF) | ||
| Diagnosis | PI-CF (Pancreas insufficient) | ||
| Diagnosis | Cystic fibrosis-related disorder | CFTR-RDs refer to a group of diseases associated with CF mutations; do not meet diagnostic criteria for CF | |
| Diagnosis | PS-CF (Pancreas sufficient) | ||
| Diagnosis | Molecular Alteration | ||
| Comorbidities | Comorbidities | ||
| Comorbidities | Pseudomonas | Pseudomonas is a clinically notable and aggressive pathogen, often causing nosocomial infections. | |
| Therapy | Lung transplantation | ||
| Therapy | Liver transplantation | ||
| Therapy | Oxygen longterm therapy | ||
| Therapy | CFTR-Modulator-Therapy | These therapies are designed to correct the malfunctioning protein made by the CFTR gene | |
| Lung Function | sRaw | Specific Airway Resistance | |
| Lung Function | sRaw% | Specific airway resistance as percentage of predicted value (sRaw%) | |
| Lung Function | TLC | Total Lung Capacity: the volume of air in the lungs at maximum inflation | |
| Lung Function | TLC% | Total Lung Capacity as percentage of the predicted value | |
| Lung Function | Rtot% | Total airway resistance as percentage of predicted value | |
| Lung Function | Rtot | Total airway resistance | |
| Lung Function | RV | Residual Volume: the amount of air remaining in the lungs after maximum exhalation | |
| Lung Function | RV% | Residual Volume as percentage of predicted value | |
| Lung Function | FVC | Forced Vital Capacity: the volume of air that can forcibly be blown out after full inspiration | |
| Lung Function | Vcmax | The largest volume a patient can exhale after a full inhalation | |
| Lung Function | FEV1 | Forced Expiratory Volume in 1 second: the volume of air that has been exhaled at the end of the first second of forced expiration | |
| Lung Function | Multiple Breath Washout | LCI | Lung Clearance Index (LCI) measured by multiple breath washout is a sensititve measure of ventilation inhomogeneity |
| Biobank Samples | Blood | The availability of blood samples for a certain patient | |
| Biobank Samples | Bronchoalveolar Lavage Fluid | The availability of Bronchoalveolar Lavage Fluid samples for a certain patient | |
| Biobank Samples | Nose swab (NS) | The availability of nose swab samples for a certain patient | |
| Biobank Samples | Sputum (SP) | The availability of sputum samples for a certain patient | |
| Laboratory values | IgG | A protein produced by plasma cells and lymphocytes and characteristics of these types of cells | |
| Laboratory values | Total IgE | Total IgE plays an important role in causing allergic reactions. | |
| Laboratory values | PsA Alkaline Protease Antibody | P. aeruginosa alkaline protease is produced during keratitis, otitis media, CF, and bacteraemia. | |
| Laboratory values | PsA Elastase Antibody | Elastase is a major virulence factor in P. aeruginosa; it cause tissue damage during infection in the human host. | |
| Laboratory values | PsA Exotoxin A Antibody | Exotoxin A is the most toxic of the numerous extracellular proteins produced by P. aeruginosa. | |
| Laboratory values | Oral glucose tolerance test (oGTT) | oGGT are used to measure how well the body can process a larger amount of sugar. | |
| Imaging | Chest X-ray performed | ||
| Imaging | MRT NNA performed | ||
| Imaging | Ultrasound |
Authors
PD Dr. Anna-Maria Dittrich, BREATH
PD Dr. Lutz Nährlich, UGMLC
PD Dr. Olaf Sommerburg, TLRC
Central Data Management
Unsere Seite verwendet Cookies und ähnliche Technologien. Mit der Nutzung der Webseite stimmen Sie der Verwendung von Cookies zu.
Mehr Informationen dazu finden Sie in unserer Datenschutzerklärung.
