Im DZL werden deutschlandweit Biomaterialproben und Daten bzw. Bilddaten von Patienten und gesunden Probanden für wissenschaftliche Zwecke erhoben. Als Grundlage dafür werden informierte Einwilligungserklärungen (Broad Informed Consent) durch Patienten und Probanden erteilt. Wir informieren diese Personengruppe mit der folgenden Übersicht, in welchen Forschungsprojekten Proben und Daten verwendet werden und welche Fragestellungen in diesen Projekten verfolgt werden.
Bei Fragen zur Proben- und Datenverwendung im DZL wenden Sie sich bitte an den DZL-Biobank-Manager, Herrn Dr. Clemens Ruppert (clemens.ruppert@innere.med.uni-giessen.de) oder an die DZL-Geschäftsstelle (contact@dzl.de).
Die Suche oberhalb der Tabelle durchsucht die gesamten Inhalte. Die Such- und Filterfelder in der Tabelle beziehen sich lediglich auf die jeweilige Spalte. Alle Filter- und Suchoptionen können miteinander kombiniert werden – so können sehr genaue Suchergebnisse erzielt werden. Durch einen Klick auf "Filter löschen" wird die Tabelle in den Ausgangszustand zurückversetzt (Achtung: Es kann vorkommen, dass Auswahlfilter nicht komplett zurückgesetzt werden. In diesem Fall müssen die Filter manuell zurückgesetzt werden oder – am einfachsten – die gesamte Seite neu geladen werden).
| Project Title | Project Title | Disease Area / Platform | DZL Site | Year | Samples and Data used | ||
|---|---|---|---|---|---|---|---|
| Project Title | Project Title | Disease Area / Platform | DOI | URL | DZL Site | Year | Samples and Data used |
| Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis. | Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis. | DPLD | 10.1136/thoraxjnl-2014-206411 | CPC-M, UGMLC | 2015 | Biosamples and Data | |
| Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling | Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling | DPLD | 10.1073/pnas.1415111112 | UGMLC | 2015 | Biosamples and Data | |
| Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. | Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. | Other | 10.1038/ncomms11626 | UGMLC | 2016 | Biosamples and Data | |
| Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. | Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. | DPLD | 10.1371/journal.pone.0207915 | UGMLC | 2018 | Biosamples and Data | |
| Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. | Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation. | DPLD | 10.1152/ajplung.00205.2017 | CPC-M | 2018 | Biosamples and Data | |
| Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis. | Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis. | DPLD | 10.1186/s12931-018-0876-y | CPC-M | 2018 | Biosamples and Data | |
| FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis | FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis | PH | 10.15252/emmm.201606261 | UGMLC | 2018 | Biosamples and Data | |
| Is the fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling? | Is the fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling? | DPLD, PH | 10.1152/ajplung.00140.2018 | UGMLC | 2018 | Biosamples and Data | |
| Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease | Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease | DPLD | 10.1038/s41467-018-06833-7 | UGMLC | 2018 | Biosamples and Data | |
| Exhalative Breath Markers Do Not Offer for Diagnosis of Interstitial Lung Diseases: Data from the European IPF Registry (eurIPFreg) and Biobank | Exhalative Breath Markers Do Not Offer for Diagnosis of Interstitial Lung Diseases: Data from the European IPF Registry (eurIPFreg) and Biobank | DPLD | 10.3390/jcm8050643 | UGMLC | 2019 | Biosamples and Data | |
| Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling. | Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling. | DPLD | 10.3791/58437 | CPC-M | 2019 | Biosamples and Data | |
| Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension | Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension | PH | 10.1073/pnas.1904064116 | UGMLC | 2019 | Biosamples and Data | |
| Proteasome activator PA200 regulates myofibroblast differentiation. | Proteasome activator PA200 regulates myofibroblast differentiation. | DPLD | 10.1038/s41598-019-51665-0 | CPC-M | 2019 | Biosamples and Data | |
| Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells | Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells | DPLD | 10.1007/s00109-019-01787-9 | UGMLC | 2019 | Biosamples and Data | |
| Shared and distinct mechanisms of fibrosis. | Shared and distinct mechanisms of fibrosis. | DPLD | 10.1038/s41584-019-0322-7 | CPC-M | 2019 | Biosamples and Data | |
| Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension | Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension | PH | 10.1038/s41467-019-10135-x | UGMLC | 2019 | Biosamples and Data | |
| TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. | TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. | DPLD | 10.1152/ajplung.00400.2018 | CPC-M | 2019 | Biosamples and Data | |
| A continuous responder algorithm to optimize clinical management of small-cell lung cancer with progastrin-releasing peptide as a simple blood test | A continuous responder algorithm to optimize clinical management of small-cell lung cancer with progastrin-releasing peptide as a simple blood test | LC | 10.1177/1010428320958603 | TLRC | 2020 | Biosamples and Data | |
| Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. | Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. | DPLD | 10.1038/s41467-020-17358-3 | CPC-M | 2020 | Biosamples and Data | |
| BAP1 Loss is a Useful Adjunct to Distinguish Malignant Mesothelioma Including the Adenomatoid-like Variant From Benign Adenomatoid Tumors | BAP1 Loss is a Useful Adjunct to Distinguish Malignant Mesothelioma Including the Adenomatoid-like Variant From Benign Adenomatoid Tumors | LC | 10.1097/PAI.0000000000000700 | TLRC | 2020 | Data | |
| Circulating Interleukin-4 Is Associated with a Systemic T Cell Response against Tumor-Associated Antigens in Treatment-Naive Patients with Resectable Non-Small-Cell Lung Cancer | Circulating Interleukin-4 Is Associated with a Systemic T Cell Response against Tumor-Associated Antigens in Treatment-Naive Patients with Resectable Non-Small-Cell Lung Cancer | LC | 10.3390/cancers12123496 | TLRC | 2020 | Biosamples and Data | |
| Comprehensive serial biobanking in advanced NSCLC: feasibility, challenges and perspectives | Comprehensive serial biobanking in advanced NSCLC: feasibility, challenges and perspectives | LC | 10.21037/tlcr-20-137 | ARCN, CPC-M, TLRC | 2020 | Biosamples and Data | |
| Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice | Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice | DPLD | 10.1038/s41467-020-15743-6 | BREATH, TLRC | 2020 | Biosamples and Data | |
| Consolidation Immunotherapy After Platinum-Based Chemoradiotherapy in Patients With Unresectable Stage III Non-Small Cell Lung Cancer-Cross-Sectional Study of Eligibility and Administration Rates | Consolidation Immunotherapy After Platinum-Based Chemoradiotherapy in Patients With Unresectable Stage III Non-Small Cell Lung Cancer-Cross-Sectional Study of Eligibility and Administration Rates | LC | 10.3389/fonc.2020.586449 | TLRC | 2020 | Data | |
| CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases. | CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases. | DPLD | 10.1183/13993003.00460-2019 | CPC-M | 2020 | Biosamples and Data | |
| Deep Learning for the Classification of Small-Cell and Non-Small-Cell Lung Cancer | Deep Learning for the Classification of Small-Cell and Non-Small-Cell Lung Cancer | LC | 10.3390/cancers12061604 | TLRC | 2020 | Data | |
| Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis | Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis | LC | 10.3390/cancers12123528 | TLRC, UGMLC | 2020 | Biosamples and Data | |
| Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas | Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas | LC | 10.3390/cells9081755 | TLRC | 2020 | Biosamples and Data | |
| Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study | Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study | LC | 10.1016/j.jtho.2020.03.023 | TLRC | 2020 | Biosamples and Data | |
| Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies | Germline Genetic Variants of the Renin-Angiotensin System, Hypoxia and Angiogenesis in Non-Small Cell Lung Cancer Progression: Discovery and Validation Studies | LC | 10.3390/cancers12123834 | TLRC | 2020 | Data | |
| Immunohistological expression of oestrogen receptor, progesterone receptor, mammaglobin, human epidermal growth factor receptor 2 and GATA-binding protein 3 in non-small-cell lung cancer | Immunohistological expression of oestrogen receptor, progesterone receptor, mammaglobin, human epidermal growth factor receptor 2 and GATA-binding protein 3 in non-small-cell lung cancer | LC | 10.1111/his.14203 | TLRC | 2020 | Data | |
| Impact of Natural or Synthetic Singletons in the Capsid of Human Bocavirus 1 on Particle Infectivity and Immunoreactivity | Impact of Natural or Synthetic Singletons in the Capsid of Human Bocavirus 1 on Particle Infectivity and Immunoreactivity | PALI | 10.1128/JVI.00170-20 | TLRC | 2020 | Biosamples | |
| Inhibition of LTβR signalling activates WNT-induced regeneration in lung. | Inhibition of LTβR signalling activates WNT-induced regeneration in lung. | DPLD | 10.1038/s41586-020-2882-8 | CPC-M | 2020 | Biosamples and Data | |
| Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56 | Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56 | LC | 10.1097/PAI.0000000000000715 | TLRC | 2020 | Data | |
| Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA | Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA | LC | 10.1016/j.ebiom.2020.103103 | ARCN, TLRC | 2020 | Biosamples and Data | |
| Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores | Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores | DPLD | 10.1016/j.matbio.2019.12.001 | UGMLC | 2020 | Biosamples and Data | |
| Mass Spectrometry Imaging for Reliable and Fast Classification of Non-Small Cell Lung Cancer Subtypes | Mass Spectrometry Imaging for Reliable and Fast Classification of Non-Small Cell Lung Cancer Subtypes | LC | 10.3390/cancers12092704 | TLRC | 2020 | Data | |
| MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically | MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically | LC | 10.1038/s41467-020-18372-1 | CPC-M, TLRC | 2020 | Data | |
| No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in March 2020 | No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in March 2020 | PALI | 10.1007/s15010-020-01471-y | BREATH | 2020 | Biosamples and Data | |
| Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis | Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis | COPD | 10.1371/journal.pone.0238619 | ARCN | 2020 | Data | |
| Notch3 Deficiency Attenuates Pulmonary Fibrosis and Impedes Lung-Function Decline. | Notch3 Deficiency Attenuates Pulmonary Fibrosis and Impedes Lung-Function Decline. | DPLD | 10.1165/rcmb.2020-0516OC | UGMLC | 2020 | Biosamples and Data | |
| Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages | Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages | LC | 10.3390/cancers12040954 | BREATH, TLRC, UGMLC | 2020 | Biosamples and Data | |
| Oligoprogressive Non-Small-Cell Lung Cancer under Treatment with PD-(L)1 Inhibitors | Oligoprogressive Non-Small-Cell Lung Cancer under Treatment with PD-(L)1 Inhibitors | LC | 10.3390/cancers12041046 | TLRC | 2020 | Data | |
| Paclitaxel for treatment of advanced small cell lung cancer (SCLC): a retrospective study of 185 patients | Paclitaxel for treatment of advanced small cell lung cancer (SCLC): a retrospective study of 185 patients | LC | 10.21037/jtd.2019.12.74 | TLRC | 2020 | Data | |
| Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia. | Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia. | PALI | 10.1016/j.vaccine.2019.11.026 | BREATH | 2020 | Biosamples and Data | |
| Precision 3D-Printed Cell Scaffolds Mimicking Native Tissue Composition and Mechanics. | Precision 3D-Printed Cell Scaffolds Mimicking Native Tissue Composition and Mechanics. | DPLD | 10.1002/adhm.202000918 | CPC-M | 2020 | Biosamples and Data | |
| Protein-altering germline mutations implicate novel genes related to lung cancer development | Protein-altering germline mutations implicate novel genes related to lung cancer development | LC | 10.1038/s41467-020-15905-6 | TLRC | 2020 | Data | |
| Rate and predictors of bacteremia in afebrile community-acquired pneumonia | Rate and predictors of bacteremia in afebrile community-acquired pneumonia | PALI | 10.1016/j.chest.2019.10.006 | BREATH | 2020 | Biosamples and Data | |
| Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer | Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer | LC | 10.1016/j.ccell.2020.05.005 | TLRC | 2020 | Data | |
| Risk stratification of EGFR(+) lung cancer diagnosed with panel-based next-generation sequencing | Risk stratification of EGFR(+) lung cancer diagnosed with panel-based next-generation sequencing | LC | 10.1016/j.lungcan.2020.08.007 | TLRC | 2020 | Data | |
| SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells | SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells | PALI | 10.15252/embj.20105114 | TLRC | 2020 | Biosamples and Data | |
| Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest andDuring Exercise | Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest andDuring Exercise | COPD | 10.2147/COPD.S217474 | BREATH | 2020 | Biosamples and Data | |
| Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial | Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial | LC | 10.1186/s12885-020-07264-8 | TLRC | 2020 | Biosamples and Data | |
| A Phase II Trial of Nivolumab With Chemotherapy Followed by Maintenance Nivolumab in Patients With Pleural Mesothelioma After Surgery: The NICITA Study Protocol | A Phase II Trial of Nivolumab With Chemotherapy Followed by Maintenance Nivolumab in Patients With Pleural Mesothelioma After Surgery: The NICITA Study Protocol | LC | 10.1016/j.cllc.2020.10.005 | TLRC | 2021 | Biosamples and Data | |
| Profibrotic epithelial TGF-beta1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN | Profibrotic epithelial TGF-beta1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN | DPLD | 10.1152/ajplung.00444.2019 | TLRC | 2021 | Biosamples and Data | |
| Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP) | Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP) | PALI | 10.1007/s15010-021-01707-5 | BREATH | 2021 | Biosamples and Data | |
| A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma | A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma | LC | 10.1080/2162402X.2020.1860586 | TLRC | 2021 | Data | |
| Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality | Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality | PALI | 10.1172/JCI152386 | BREATH | 2021 | Biosamples and Data | |
| Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort | Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort | AA | 10.1111/cea.13964 | ARCN | 2021 | Biosamples and Data | |
| An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices | An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices | DPLD | 10.1183/13993003.00221-2020 | TLRC | 2021 | Biosamples and Data | |
| Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease | Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease | PALI | 10.1371/journal.pone.0258684 | UGMLC | 2021 | Biosamples and Data | |
| Association of the advanced lung cancer inflammation index (ALI) with immune checkpoint inhibitor efficacy in patients with advanced non-small-cell lung cancer | Association of the advanced lung cancer inflammation index (ALI) with immune checkpoint inhibitor efficacy in patients with advanced non-small-cell lung cancer | LC | 10.1016/j.esmoop.2021.100254 | TLRC | 2021 | Data | |
| Behandlung von erwachsenen Patienten mit ambulant erworbener Pneumonie – Update 2021 | Behandlung von erwachsenen Patienten mit ambulant erworbener Pneumonie – Update 2021 | PALI | 10.1055/a-1497-0693 | BREATH | 2021 | Biosamples and Data | |
| Brigatinib versus other second-generation ALK inhibitors as initial treatment of anaplastic lymphoma kinase positive non-small cell lung cancer with deep phenotyping: study protocol of the ABP trial | Brigatinib versus other second-generation ALK inhibitors as initial treatment of anaplastic lymphoma kinase positive non-small cell lung cancer with deep phenotyping: study protocol of the ABP trial | LC | 10.1186/s12885-021-08460-w | TLRC | 2021 | Biosamples and Data | |
| Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia | Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia | PALI | 10.1136/gutjnl-2020-320876 | BREATH | 2021 | Biosamples and Data | |
| Comprehensive Dissection of Treatment Patterns and Outcome for Patients With Metastatic Large-Cell Neuroendocrine Lung Carcinoma | Comprehensive Dissection of Treatment Patterns and Outcome for Patients With Metastatic Large-Cell Neuroendocrine Lung Carcinoma | LC | 10.3389/fonc.2021.673901 | TLRC | 2021 | Data | |
| Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma | Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma | LC | 10.21037/tlcr-20-1168 | ARCN, TLRC | 2021 | Data | |
| COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19 | COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19 | PALI | 10.1038/s41586-021-03767-x | BREATH | 2021 | Biosamples and Data | |
| Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time | Cytokine levels in children and adults with wheezing and asthma show specific patterns of variability over time | AA | 10.1111/cei.13550 | ARCN | 2021 | Biosamples and Data | |
| De Novo Versus Secondary Metastatic EGFR-Mutated Non-Small-Cell Lung Cancer | De Novo Versus Secondary Metastatic EGFR-Mutated Non-Small-Cell Lung Cancer | LC | 10.3389/fonc.2021.640048 | TLRC | 2021 | Data | |
| Decellularized Human Lung Scaffolds as Complex Three-Dimensional Tissue Culture Models to Study Functional Behavior of Fibroblasts. | Decellularized Human Lung Scaffolds as Complex Three-Dimensional Tissue Culture Models to Study Functional Behavior of Fibroblasts. | DPLD | 10.1007/978-1-0716-1382-5_30 | CPC-M | 2021 | Biosamples and Data | |
| Differential Regulation of Interferon Signaling Pathways in CD4+ T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype | Differential Regulation of Interferon Signaling Pathways in CD4+ T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype | AA | 10.3390/ijms221810144 | UGMLC | 2021 | Biosamples and Data | |
| Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs | Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs | PALI | 10.3389/fmed.2021.749588 | BREATH | 2021 | Biosamples and Data | |
| DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer | DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer | LC | 10.1186/s13148-021-01024-6 | ARCN, TLRC | 2021 | Biosamples and Data | |
| Earlier extracranial progression and shorter survival in ALK-rearranged lung cancer with positive liquid rebiopsies | Earlier extracranial progression and shorter survival in ALK-rearranged lung cancer with positive liquid rebiopsies | LC | 10.21037/tlcr-21-32 | TLRC | 2021 | Biosamples and Data | |
| Early Changes and Indicators Characterizing Lung Aging in Neonatal Chronic Lung Disease. | Early Changes and Indicators Characterizing Lung Aging in Neonatal Chronic Lung Disease. | DPLD | 10.3389/fmed.2021.665152 | CPC-M | 2021 | Biosamples and Data | |
| Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis | Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis | LC | 10.1038/s41698-021-00239-3 | ARCN, TLRC | 2021 | Biosamples and Data | |
| Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 | Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 | PALI | 10.1016/j.immuni.2021.09.002 | BREATH | 2021 | Biosamples and Data | |
| Evaluation of a multiplex PCR screening approach to identify community-acquired bacterial co-infections in COVID-19: a multicenter prospective cohort study of the German competence network of community-acquired pneumonia (CAPNETZ) | Evaluation of a multiplex PCR screening approach to identify community-acquired bacterial co-infections in COVID-19: a multicenter prospective cohort study of the German competence network of community-acquired pneumonia (CAPNETZ) | PALI | 10.1007/s15010-021-01720-8 | BREATH | 2021 | Biosamples and Data | |
| Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross reactivity | Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross reactivity | PALI | 10.1038/s41467-021-20973-3 | BREATH | 2021 | Biosamples and Data | |
| Follicular Helper-like T Cells in the Lung Highlight a Novel Role of B Cells in Sarcoidosis | Follicular Helper-like T Cells in the Lung Highlight a Novel Role of B Cells in Sarcoidosis | DPLD | 10.1164/rccm.202012-4423OC | UGMLC | 2021 | Biosamples and Data | |
| Hyperoxia/Hypoxia Exposure Primes a Sustained Pro-Inflammatory Profile of Preterm Infant Macrophages Upon LPS Stimulation. | Hyperoxia/Hypoxia Exposure Primes a Sustained Pro-Inflammatory Profile of Preterm Infant Macrophages Upon LPS Stimulation. | DPLD | 10.3389/fimmu.2021.762789 | CPC-M | 2021 | Biosamples and Data | |
| Immune Responsiveness to LPS Determines Risk of Childhood Wheeze and Asthma in 17q21 Risk Allele Carriers | Immune Responsiveness to LPS Determines Risk of Childhood Wheeze and Asthma in 17q21 Risk Allele Carriers | AA | 10.1164/rccm.202106-1458OC | UGMLC | 2021 | Biosamples and Data | |
| Impaired function and delayed regeneration of dendritic cells in COVID-19. | Impaired function and delayed regeneration of dendritic cells in COVID-19. | DPLD | 10.1371/journal.ppat.1009742 | CPC-M | 2021 | Biosamples and Data | |
| In silico numerical simulation of ventilator settings during high-frequency ventilation in preterm infants. | In silico numerical simulation of ventilator settings during high-frequency ventilation in preterm infants. | DPLD | 10.1002/ppul.25626 | CPC-M | 2021 | Biosamples and Data | |
| Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers. | Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers. | DPLD | 10.15252/emmm.202012871 | CPC-M | 2021 | Biosamples and Data | |
| Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican | Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican | LC | 10.3390/cancers13020208 | TLRC, UGMLC | 2021 | Biosamples and Data | |
| Interobserver agreement in interpretation of chest radiographs for pediatric community acquired pneumonia: Findings of the pedCAPNETZ-cohort | Interobserver agreement in interpretation of chest radiographs for pediatric community acquired pneumonia: Findings of the pedCAPNETZ-cohort | PALI | 10.1002/PPUL.25528 | BREATH | 2021 | Biosamples and Data | |
| Mapping the human genetic architecture of COVID-19 | Mapping the human genetic architecture of COVID-19 | PALI | 10.1038/s41586-021-03767-x | ARCN | 2021 | Biosamples and Data | |
| Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. | Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling. | DPLD | 10.1021/acs.jproteome.0c00641 | CPC-M | 2021 | Biosamples and Data | |
| Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: First clinical experience | Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: First clinical experience | LC | 10.1016/j.lungcan.2021.01.018 | TLRC | 2021 | Data | |
| Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics. | Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics. | DPLD | 10.1126/sciadv.abb3673 | CPC-M | 2021 | Biosamples and Data | |
| Prognostic Impact of PD-L1 Expression in pN1 NSCLC: A Retrospective Single-Center Analysis | Prognostic Impact of PD-L1 Expression in pN1 NSCLC: A Retrospective Single-Center Analysis | LC | 10.3390/cancers13092046 | TLRC | 2021 | Data | |
| Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung. | Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung. | DPLD | 10.1038/s41586-020-03087-6 | CPC-M | 2021 | Biosamples and Data | |
| Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer | Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer | LC | 10.1177/1758835921996509 | TLRC | 2021 | Data | |
| Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples | Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples | LC | 10.1186/s12885-021-08140-9 | TLRC | 2021 | Data | |
| Sarcopenia on preoperative chest computed tomography predicts cancer-specific and all-cause mortality following pneumonectomy for lung cancer: A multicenter analysis | Sarcopenia on preoperative chest computed tomography predicts cancer-specific and all-cause mortality following pneumonectomy for lung cancer: A multicenter analysis | LC | 10.1002/cam4.4207 | TLRC | 2021 | Data | |
| Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. | Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. | DPLD | 10.1172/jci.insight.150862 | CPC-M | 2021 | Biosamples and Data | |
| Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community-acquired pneumonia | Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community-acquired pneumonia | PALI | 10.1152/ajplung.00162.2021 | BREATH | 2021 | Biosamples and Data | |
| Shift in bacterial etiology from the CAPNETZ cohort in patients with community-acquired pneumonia: data over more than a decade | Shift in bacterial etiology from the CAPNETZ cohort in patients with community-acquired pneumonia: data over more than a decade | PALI | 10.1007/s15010-021-01605-w | BREATH | 2021 | Biosamples and Data | |
| Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. | Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. | DPLD | 10.1038/s41467-021-24730-4 | CPC-M | 2021 | Biosamples and Data | |
| Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population | Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population | PALI | 10.1177/17534259211029996 | BREATH | 2021 | Biosamples and Data | |
| Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials | Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials | Other | 10.1002/SMSC.202100067 | ARCN | 2021 | Biosamples and Data | |
| Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension | Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension | PH | 10.1165/rcmb.2019-0431OC | UGMLC | 2021 | Biosamples and Data | |
| The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma | The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma | LC | 10.1016/j.esmoop.2021.100253 | TLRC | 2021 | Data | |
| The impact of the SARS-CoV-2 pandemic on the prevalence of respiratory tract pathogens in patients with community-acquired pneumonia in Germany | The impact of the SARS-CoV-2 pandemic on the prevalence of respiratory tract pathogens in patients with community-acquired pneumonia in Germany | PALI | 10.1080/22221751.2021.1957402 | BREATH | 2021 | Biosamples and Data | |
| Therapeutic and Prognostic Implications of Immune-Related Adverse Events in Advanced Non-Small-Cell Lung Cancer | Therapeutic and Prognostic Implications of Immune-Related Adverse Events in Advanced Non-Small-Cell Lung Cancer | LC | 10.3389/fonc.2021.703893 | TLRC | 2021 | Data | |
| Validation of the T Descriptor (TNM-8) in T3N0 Non-Small-Cell Lung Cancer Patients; a Bicentric Cohort Analysis with Arguments for Redefinition | Validation of the T Descriptor (TNM-8) in T3N0 Non-Small-Cell Lung Cancer Patients; a Bicentric Cohort Analysis with Arguments for Redefinition | LC | 10.3390/cancers13081812 | TLRC | 2021 | Data | |
| Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung | Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung | COPD | 10.1172/jci.insight.140443 | CPC-M, TLRC | 2021 | Biosamples and Data | |
| Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients. | Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients. | DPLD | 10.1016/j.bbadis.2022.166592 | CPC-M | 2022 | Biosamples and Data | |
| Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells. | Validation of in vitro models for smoke exposure of primary human bronchial epithelial cells. | DPLD | 10.1152/ajplung.00091.2021 | CPC-M | 2022 | Biosamples and Data | |
| Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections | Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections | PALI | 10.2807/1560-7917.ES.2022.27.43.2101089 | BREATH | 2022 | Biosamples and Data | |
| Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19 | Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19 | PALI | 10.1016/j.isci.2022.103760 | BREATH | 2022 | Biosamples and Data | |
| A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy | A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy | LC | 10.1038/s41698-022-00262-y | ARCN, TLRC | 2022 | Biosamples and Data | |
| A longitudinal analysis of pneumococcal vaccine serotypes in pneumonia patients in Germany | A longitudinal analysis of pneumococcal vaccine serotypes in pneumonia patients in Germany | PALI | 10.1183/13993003.02432-2021 | BREATH | 2022 | Biosamples and Data | |
| Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy. | Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy. | DPLD | 10.1183/13993003.01798-2021 | CPC-M | 2022 | Biosamples and Data | |
| Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study | Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study | LC | 10.3389/fonc.2022.772076 | TLRC | 2022 | Biosamples and Data | |
| Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects. | Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects. | DPLD | 10.3390/pharmaceutics14030671 | CPC-M | 2022 | Biosamples and Data | |
| An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea | An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea | DPLD | 10.1242/dev.199804 | UGMLC | 2022 | Biosamples and Data | |
| Association of immune cell recruitment and BPD development. | Association of immune cell recruitment and BPD development. | DPLD | 10.1186/s40348-022-00148-w | CPC-M | 2022 | Biosamples and Data | |
| Canine real-time detection of SARS-CoV-2 infections in the context of a mass screening even | Canine real-time detection of SARS-CoV-2 infections in the context of a mass screening even | PALI | 10.1136/bmjgh-2022-010276 | BREATH | 2022 | Biosamples and Data | |
| Cell-Surface Programmed Death Ligand-1 Expression Identifies a Sub-Population of Distal Epithelial Cells Enriched in Idiopathic Pulmonary Fibrosis | Cell-Surface Programmed Death Ligand-1 Expression Identifies a Sub-Population of Distal Epithelial Cells Enriched in Idiopathic Pulmonary Fibrosis | DPLD | 10.3390/cells11101593 | UGMLC | 2022 | Biosamples and Data | |
| Cellular dissociation grading on biopsies of pulmonary squamous cell carcinoma provides prognostic information across all stages and is congruent with resection specimen grading | Cellular dissociation grading on biopsies of pulmonary squamous cell carcinoma provides prognostic information across all stages and is congruent with resection specimen grading | LC | 10.1002/cjp2.295 | TLRC, CPC-M | 2022 | Biosamples and Data | |
| Circulating hyaluronic acid signature in CAP and ARDS – the role of pneumolysin in hyaluronic acid shedding | Circulating hyaluronic acid signature in CAP and ARDS – the role of pneumolysin in hyaluronic acid shedding | PALI | 10.1016/J.MATBIO.2022.11.003 | BREATH | 2022 | Biosamples and Data | |
| Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany | Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany | PALI | 10.3389/fimmu.2022.828053 | BREATH | 2022 | Biosamples and Data | |
| Continuous Rather Than Solely Early Farm Exposure Protects From Hay Fever Development | Continuous Rather Than Solely Early Farm Exposure Protects From Hay Fever Development | AA | 10.1016/j.jaip.2022.10.035 | UGMLC | 2022 | Biosamples and Data | |
| Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer | Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer | LC | 10.1038/s41588-022-01115-x | TLRC | 2022 | Data | |
| Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma | Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma | LC | 10.1007/s00262-021-02981-w | ARCN, CPC-M, TLRC | 2022 | Biosamples and Data | |
| Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections | Deep learning for the detection of anatomical tissue structures and neoplasms of the skin on scanned histopathological tissue sections | LC | 10.3389/fonc.2022.1022967 | TLRC | 2022 | Data | |
| Detailed stratified GWAS analysis for severe COVID-19 in four European populations | Detailed stratified GWAS analysis for severe COVID-19 in four European populations | PALI | 10.1093/hmg/ddac158 | ARCN, BREATH | 2022 | Biosamples and Data | |
| Development and validation of a sensitive and robust multiplex antigen capture assay to quantify Streptococcus pneumoniae serotype-specific capsular polysaccharides in urine | Development and validation of a sensitive and robust multiplex antigen capture assay to quantify Streptococcus pneumoniae serotype-specific capsular polysaccharides in urine | PALI | 10.1128/msphere.00114-22 | BREATH | 2022 | Biosamples and Data | |
| Differential LysoTracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis. | Differential LysoTracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis. | DPLD | 10.3390/cells11020235 | UGMLC | 2022 | Biosamples and Data | |
| Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers | Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers | LC | 10.1080/15592294.2021.1878723 | TLRC | 2022 | Biosamples and Data | |
| Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells | Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells | CFBE, LC | 10.1080/15592294.2021.1959976 | TLRC | 2022 | Biosamples and Data | |
| Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly | Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly | PALI | 10.1038/s41467-022-34487-z | BREATH | 2022 | Biosamples and Data | |
| Early Assessment of Chemotherapy Response in Advanced Non-Small Cell Lung Cancer with Circulating Tumor DNA | Early Assessment of Chemotherapy Response in Advanced Non-Small Cell Lung Cancer with Circulating Tumor DNA | LC | 10.3390/cancers14102479 | TLRC | 2022 | Biosamples and Data | |
| Early post-discharge mortality in CAP: frequency, risk factors and a prediction tool | Early post-discharge mortality in CAP: frequency, risk factors and a prediction tool | PALI | 10.1007/s10096-022-04416-5 | BREATH | 2022 | Biosamples and Data | |
| Editorial: Defining and Characterizing Respiratory Disease in an Aging Population. | Editorial: Defining and Characterizing Respiratory Disease in an Aging Population. | DPLD | 10.3389/fmed.2022.889834 | CPC-M | 2022 | Biosamples and Data | |
| Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models. | Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models. | DPLD | 10.3389/fcimb.2022.958634 | CPC-M | 2022 | Biosamples and Data | |
| Emerging Roles of Airway Epithelial Cells in Idiopathic Pulmonary Fibrosis. | Emerging Roles of Airway Epithelial Cells in Idiopathic Pulmonary Fibrosis. | DPLD | 10.3390/cells11061050 | CPC-M | 2022 | Biosamples and Data | |
| Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension | Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension | PH | 10.1126/scitranslmed.abe5407 | UGMLC | 2022 | Biosamples and Data | |
| Establishment of a Tissue-Mimicking Surrogate for Pulmonary Lesions to Improve the Development of RFA Instruments and Algorithms | Establishment of a Tissue-Mimicking Surrogate for Pulmonary Lesions to Improve the Development of RFA Instruments and Algorithms | LC | 10.3390/biomedicines10051100 | TLRC | 2022 | Biosamples and Data | |
| FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis Cells. | FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis Cells. | DPLD | 10.3390/cells11081341 | CPC-M, UGMLC | 2022 | Biosamples and Data | |
| Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer | Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer | LC | 10.1186/s40001-022-00638-7 | TLRC | 2022 | Biosamples and Data | |
| Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases | Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases | PALI | 10.1128/jvi.00098-22 | TLRC | 2022 | Biosamples | |
| Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS) | Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS) | LC | 10.3390/ijms231810699 | TLRC | 2022 | Biosamples and Data | |
| IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction | IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction | AA | 10.1183/13993003.02130-2021 | ARCN | 2022 | Biosamples and Data | |
| Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes. | Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes. | DPLD | 10.1016/j.jconrel.2022.03.051 | CPC-M | 2022 | Biosamples and Data | |
| In-hospital mortality of patients with severe bloodstream infection: Only the tip of the iceberg | In-hospital mortality of patients with severe bloodstream infection: Only the tip of the iceberg | PALI | 10.1016/S1473-3099(21)00619-8 | BREATH | 2022 | Biosamples and Data | |
| Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers | Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers | LC | 10.1158/0008-5472.CAN-21-3836 | TLRC | 2022 | Biosamples and Data | |
| Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients | Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients | LC | 10.1186/s13148-022-01387-4 | ARCN, TLRC | 2022 | Biosamples and Data | |
| Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene | Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene | LC | 10.3390/cancers14184454 | BREATH, TLRC | 2022 | Biosamples and Data | |
| Multimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach | Multimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach | LC | 10.21037/tlcr-22-199 | TLRC | 2022 | Data | |
| Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. | Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. | PH | 10.1161/CIRCRESAHA.121.319100 | UGMLC | 2022 | Biosamples and Data | |
| Plasma markers of COVID-19 severity: a pilot study | Plasma markers of COVID-19 severity: a pilot study | PALI | 10.1186/s12931-022-02272-7 | BREATH | 2022 | Biosamples and Data | |
| Protocol of the TREASURE study: Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease - a randomized, open-label, multicenter phase II trial | Protocol of the TREASURE study: Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease - a randomized, open-label, multicenter phase II trial | LC | 10.1186/s12885-022-10074-9 | TLRC | 2022 | Biosamples and Data | |
| Psychometric validation of the German translation of the Quality of Life Questionnaire – Bronchiectasis (QOL-B): Data from the German bronchiectasis registry PROGNOSIS. | Psychometric validation of the German translation of the Quality of Life Questionnaire – Bronchiectasis (QOL-B): Data from the German bronchiectasis registry PROGNOSIS. | PALI | 10.3390/jcm11020441 | BREATH | 2022 | Data | |
| Real-Time Measurement of Cell Mechanics as a Clinically Relevant Readout of an In Vitro Lung Fibrosis Model Established on a Bioinspired Basement Membrane. | Real-Time Measurement of Cell Mechanics as a Clinically Relevant Readout of an In Vitro Lung Fibrosis Model Established on a Bioinspired Basement Membrane. | DPLD | 10.1002/adma.202205083 | CPC-M | 2022 | Biosamples and Data | |
| Reduction of BMPR2 mRNA Expression in Peripheral Blood of Pulmonary Arterial Hypertension Patients: A Marker for Disease Severity? | Reduction of BMPR2 mRNA Expression in Peripheral Blood of Pulmonary Arterial Hypertension Patients: A Marker for Disease Severity? | PH | 10.3390/genes13050759 | TLRC | 2022 | Biosamples and Data | |
| Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant. | Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant. | DPLD | 10.1136/thoraxjnl-2021-218083 | CPC-M | 2022 | Biosamples and Data | |
| Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease | Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease | PALI | 10.3390/cells11152283 | BREATH | 2022 | Biosamples and Data | |
| Robust subtyping of non-small cell lung cancer whole sections through MALDI mass spectrometry imaging | Robust subtyping of non-small cell lung cancer whole sections through MALDI mass spectrometry imaging | LC | 10.1002/prca.202100068 | TLRC | 2022 | Biosamples and Data | |
| Serum cytokines predict efficacy and toxicity, but are not useful for disease monitoring in lung cancer treated with PD-(L)1 inhibitors | Serum cytokines predict efficacy and toxicity, but are not useful for disease monitoring in lung cancer treated with PD-(L)1 inhibitors | LC | 10.3389/fonc.2022.1010660 | TLRC | 2022 | Biosamples and Data | |
| Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery. | Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery. | DPLD | 10.1016/j.jconrel.2022.09.021 | CPC-M | 2022 | Biosamples and Data | |
| Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients | Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients | PALI | 10.1038/s41597-022-01669-9 | BREATH | 2022 | Biosamples and Data | |
| Surfactant protein A enhances the degradation of LPS-induced TLR4 in primary alveolar macrophages involving Rab7, β-arrestin2, and mTORC1 | Surfactant protein A enhances the degradation of LPS-induced TLR4 in primary alveolar macrophages involving Rab7, β-arrestin2, and mTORC1 | Other | 10.1128/IAI.00250-21 | ARCN | 2022 | Biosamples and Data | |
| T2-high asthma phenotypes across lifespan | T2-high asthma phenotypes across lifespan | AA | 10.1183/13993003.02288-2021 | ARCN | 2022 | Biosamples and Data | |
| Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread. | Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread. | DPLD | 10.1093/nar/gkab1248 | CPC-M | 2022 | Biosamples and Data | |
| Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension | Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension | PH | 10.1183/13993003.01698-2021 | UGMLC | 2022 | Biosamples and Data | |
| The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling | The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling | PALI | 10.1016/j.ebiom.2022 | BREATH | 2022 | Biosamples and Data | |
| The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics | The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics | PALI | 10.1007/s10654-022-00896-z | BREATH | 2022 | Biosamples and Data | |
| TRAIL protects the immature lung from hyperoxic injury. | TRAIL protects the immature lung from hyperoxic injury. | DPLD | 10.1038/s41419-022-05072-5 | CPC-M | 2022 | Biosamples and Data | |
| Trajectories of cough without a cold in early childhood and associations with atopic diseases | Trajectories of cough without a cold in early childhood and associations with atopic diseases | AA | 10.1111/cea.14257 | CPC-M | 2022 | Biosamples and Data | |
| Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis | Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis | DPLD | 10.3390/cells11121973 | UGMLC | 2022 | Biosamples and Data | |
| Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma | Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma | LC | 10.3892/ijo.2022.5329 | BREATH, TLRC | 2022 | Biosamples and Data | |
| Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis | Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis | PALI | 10.1021/acsinfecdis.2c00075 | ARCN | 2022 | Biosamples and Data | |
| Tumour cell budding and spread through air spaces in squamous cell carcinoma of the lung - Determination and validation of optimal prognostic cut-offs | Tumour cell budding and spread through air spaces in squamous cell carcinoma of the lung - Determination and validation of optimal prognostic cut-offs | LC | 10.1016/j.lungcan.2022.04.012 | TLRC | 2022 | Data | |
| Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group | Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group | PALI | 10.1186/s12931-022-02117-3 | BREATH | 2022 | Data | |
| WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme | WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme | DPLD | 10.1073/pnas.2201707119 | UGMLC | 2022 | Biosamples and Data | |
| Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia. | Validation of disease-specific biomarkers for the early detection of bronchopulmonary dysplasia. | DPLD | 10.1038/s41390-022-02093-w | CPC-M | 2023 | Biosamples and Data | |
| ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. | ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. | LC | 10.15252/embj.2022111620 | UGMLC | 2023 | Biosamples and Data | |
| Combined Pulmonary Fibrosis and Emphysema: When Scylla and Charybdis | Combined Pulmonary Fibrosis and Emphysema: When Scylla and Charybdis | COPD, DPLD | 10.3390/cells12091278 | UGMLC | 2023 | Biosamples and Data | |
| Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation. | Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation. | PH | 10.1161/CIRCRESAHA.122.321836 | UGMLC | 2023 | Biosamples and Data | |
| Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis . | Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis . | COPD, DPLD | 10.1164/rccm.202105-1284OC | UGMLC | 2023 | Biosamples and Data | |
| A second update on mapping the human genetic architecture of COVID-19. | A second update on mapping the human genetic architecture of COVID-19. | PALI | 10.1038/s41586-023-06355-3 | ARCN | 2023 | Biosamples and Data | |
| Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19 | Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19 | PALI | 10.1016/j.xgen.2022.100232 | BREATH | 2023 | Biosamples and Data | |
| An Inhibitory Function of TRPA1 Channels in TGF-β1-driven Fibroblast-to-Myofibroblast Differentiation. | An Inhibitory Function of TRPA1 Channels in TGF-β1-driven Fibroblast-to-Myofibroblast Differentiation. | DPLD | 10.1165/rcmb.2022-0159OC | CPC-M | 2023 | Biosamples and Data | |
| An integrated cell atlas of the lung in health and disease. | An integrated cell atlas of the lung in health and disease. | DPLD | 10.1038/s41591-023-02327-2 | CPC-M | 2023 | Biosamples and Data | |
| Antiviral CD8+ T cell immune responses are impaired by cigarette smoke and in COPD | Antiviral CD8+ T cell immune responses are impaired by cigarette smoke and in COPD | COPD | 10.1183/13993003.01374-2022 | ARCN | 2023 | Biosamples and Data | |
| Antiviral CD8+ T-cell immune responses are impaired by cigarette smoke and in COPD. | Antiviral CD8+ T-cell immune responses are impaired by cigarette smoke and in COPD. | DPLD | 10.1183/13993003.01374-2022 | CPC-M | 2023 | Biosamples and Data | |
| Assessment of Collagen in Translational Models of Lung Research. | Assessment of Collagen in Translational Models of Lung Research. | DPLD | 10.1007/978-3-031-26625-6_11 | CPC-M | 2023 | Biosamples and Data | |
| CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD | CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD | COPD | 10.1164/rccm.202208-1603OC | UGMLC | 2023 | Biosamples and Data | |
| Comparison of the sensitivity of different criteria to select lung cancer patients for screening in a cohort of German patients | Comparison of the sensitivity of different criteria to select lung cancer patients for screening in a cohort of German patients | LC | 10.1002/cam4.5638 | ARCN, BREATH, CPC-M, TLRC, UGMLC | 2023 | Data | |
| Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures. | Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures. | DPLD | 10.3389/fimmu.2023.1128239 | CPC-M | 2023 | Biosamples and Data | |
| Differences in Treatment Response in Bronchial Epithelial Cells from Idiopathic Pulmonary Fibrosis (IPF) Patients: A First Step towards Personalized Medicine? | Differences in Treatment Response in Bronchial Epithelial Cells from Idiopathic Pulmonary Fibrosis (IPF) Patients: A First Step towards Personalized Medicine? | DPLD | 10.3390/antiox12020443 | TLRC | 2023 | Biosamples and Data | |
| Early Detection of Lung Cancer Using Small RNAs | Early Detection of Lung Cancer Using Small RNAs | LC | 10.1016/j.jtho.2023.07.005 | ARCN, TLRC | 2023 | Biosamples and Data | |
| Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany | Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany | PALI | 10.1186/s12910-023-00959-0 | BREATH | 2023 | Biosamples and Data | |
| Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis. | Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis. | DPLD | 10.1126/scitranslmed.adh0908 | CPC-M | 2023 | Biosamples and Data | |
| Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27. | Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27. | COPD, DPLD | 10.1073/pnas.2215421120 | UGMLC | 2023 | Biosamples and Data | |
| Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice. | Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice. | COPD, PH | 10.1183/13993003.01606-2022 | UGMLC | 2023 | Biosamples and Data | |
| Genetic and geographic influence on phenotypic variation in European sarcoidosis patients | Genetic and geographic influence on phenotypic variation in European sarcoidosis patients | DPLD | 10.3389/fmed.2023.1218106 | ARCN | 2023 | Biosamples and Data | |
| Genetic Predisposition to Neurological Complications in Patients with COVID-19 | Genetic Predisposition to Neurological Complications in Patients with COVID-19 | PALI | 10.3390/biom13010133 | BREATH | 2023 | Biosamples and Data | |
| High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD | High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD | COPD | 10.15252/embj.2022111272 | TLRC, CPC-M | 2023 | Biosamples and Data | |
| Immune mapping of human tuberculosis and sarcoidosis lung granulomas | Immune mapping of human tuberculosis and sarcoidosis lung granulomas | PALI | 10.3389/fimmu.2023.1332733 | ARCN | 2023 | Biosamples and Data | |
| Impact of Coronavirus Disease 2019 on Hospital Admissions, Health Status, and Behavioral Changes of Patients with COPD | Impact of Coronavirus Disease 2019 on Hospital Admissions, Health Status, and Behavioral Changes of Patients with COPD | COPD | 10.15326/jcopdf.2022.0383 | BREATH | 2023 | Biosamples and Data | |
| Integrated circulating tumour DNA and cytokine analysis for therapy monitoring of ALK-rearranged lung adenocarcinoma | Integrated circulating tumour DNA and cytokine analysis for therapy monitoring of ALK-rearranged lung adenocarcinoma | LC | 10.1038/s41416-023-02284-0 | ARCN, TLRC | 2023 | Biosamples and Data | |
| Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients? | Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients? | PH | 10.1002/pul2.12242 | BREATH, TLRC | 2023 | Biosamples and Data | |
| Lung Adenocarcinoma Diagnosed at a Younger Age Is Associated with Advanced Stage, Female Sex, and Ever-Smoker Status, in Patients Treated with Lung Resection | Lung Adenocarcinoma Diagnosed at a Younger Age Is Associated with Advanced Stage, Female Sex, and Ever-Smoker Status, in Patients Treated with Lung Resection | LC | 10.3390/cancers15082395 | TLRC | 2023 | Data | |
| Mass spectrometry-based autoimmune profiling reveals predictive autoantigens in idiopathic pulmonary fibrosis. | Mass spectrometry-based autoimmune profiling reveals predictive autoantigens in idiopathic pulmonary fibrosis. | DPLD | 10.1016/j.isci.2023.108345 | CPC-M | 2023 | Biosamples and Data | |
| MicroRNA-223 dampens pulmonary inflammation during pneumococcal pneumonia | MicroRNA-223 dampens pulmonary inflammation during pneumococcal pneumonia | PALI | 10.3390/cells12060959 | BREATH | 2023 | Biosamples and Data | |
| MRI pulmonary artery flow detects lung vascular pathology in preterms with lung disease. | MRI pulmonary artery flow detects lung vascular pathology in preterms with lung disease. | DPLD | 10.1183/13993003.02445-2022 | CPC-M | 2023 | Biosamples and Data | |
| Neurofilament light chain levels predict encephalopathy and outcome in community-acquired pneumonia | Neurofilament light chain levels predict encephalopathy and outcome in community-acquired pneumonia | PALI | 10.1002/ACN3.51711 | BREATH | 2023 | Biosamples and Data | |
| Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations. | Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations. | COPD | 10.1183/13993003.00951-2022 | UGMLC | 2023 | Biosamples and Data | |
| Pathogen spectra in hospitalised and nonhospitalised children with community-acquired pneumonia | Pathogen spectra in hospitalised and nonhospitalised children with community-acquired pneumonia | PALI | 10.1183/23120541.00286-2022 | BREATH | 2023 | Biosamples and Data | |
| Pericentromeric satellite lncRNAs are induced in cancer- associated fibroblasts and regulate their functions in lung tumorigenesis | Pericentromeric satellite lncRNAs are induced in cancer- associated fibroblasts and regulate their functions in lung tumorigenesis | LC | 10.1038/s41419-023-05553-1 | UGMLC | 2023 | Biosamples and Data | |
| Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score | Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score | LC | 10.1007/s12672-023-00799-9 | ARCN, TLRC, UGMLC | 2023 | Biosamples and Data | |
| Prognostic Impact of the Immune-Cell Infiltrate in N1-Positive Non-Small-Cell Lung Cancer | Prognostic Impact of the Immune-Cell Infiltrate in N1-Positive Non-Small-Cell Lung Cancer | LC | 10.1016/j.cllc.2023.06.013 | TLRC, UGMLC | 2023 | Biosamples and Data | |
| Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection. | Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection. | DPLD | 10.3389/fmicb.2022.957830 | CPC-M | 2023 | Biosamples and Data | |
| Single-cell RNA sequencing of human lung innate lymphoid cells in the vascular and tissue niche reveals molecular features of tissue adaptation. | Single-cell RNA sequencing of human lung innate lymphoid cells in the vascular and tissue niche reveals molecular features of tissue adaptation. | DPLD | 10.1093/discim/kyad007 | CPC-M | 2023 | Biosamples and Data | |
| Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma. | Targeted GATA3 knockdown in activated T cells via pulmonary siRNA delivery as novel therapy for allergic asthma. | DPLD | 10.1016/j.jconrel.2023.01.014 | CPC-M | 2023 | Biosamples and Data | |
| The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2 | The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2 | DPLD | 10.1073/pnas.2213715120 | ARCN | 2023 | Biosamples and Data | |
| The ratio of neutrophil-to-lymphocyte and platelet-to-lymphocyte and association with mortality in community-acquired pneumonia: a derivation-validation cohort study | The ratio of neutrophil-to-lymphocyte and platelet-to-lymphocyte and association with mortality in community-acquired pneumonia: a derivation-validation cohort study | PALI | 10.1007/s15010-023-01992-2 | BREATH | 2023 | Biosamples and Data | |
| The scverse project provides a computational ecosystem for single-cell omics data analysis. | The scverse project provides a computational ecosystem for single-cell omics data analysis. | DPLD | 10.1038/s41587-023-01733-8 | CPC-M | 2023 | Biosamples and Data | |
| Transferability and reproducibility of exposed air-liquid interface co-culture lung models. | Transferability and reproducibility of exposed air-liquid interface co-culture lung models. | DPLD | 10.1016/j.impact.2023.100466 | CPC-M | 2023 | Biosamples and Data | |
| Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort | Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort | AA | 10.1016/j.jaci.2023.01.027 | ARCN | 2023 | Biosamples and Data | |
| Pathogen spectrum of community-acquired pneumonia in people living with HIV (PLWH) in the German CAPNETZ cohort | Pathogen spectrum of community-acquired pneumonia in people living with HIV (PLWH) in the German CAPNETZ cohort | PALI | 10.1007/s15010-023-02070-3 | BREATH | 2024 | Biosamples and Data | |
| 17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma. | 17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma. | AA | 10.1164/rccm.202305-0934OC | ARCN | 2024 | Biosamples and Data | |
| A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients | A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients | PALI | 10.1038/s41598-024-66288-3 | BREATH | 2024 | Biosamples and Data | |
| A precise performance-based reimbursement model for the multi-centre NAPKON cohorts - development and evaluation | A precise performance-based reimbursement model for the multi-centre NAPKON cohorts - development and evaluation | PALI | 10.1038/s41598-024-63945-5 | BREATH | 2024 | Biosamples and Data | |
| A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens | A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens | LC | 10.1186/s12014-024-09501-9 | TLRC | 2024 | Biosamples and Data | |
| Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection | Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection | PALI | 10.1128/mbio.03408-23 | BREATH | 2024 | Biosamples and Data | |
| Adiponectin suppresses stiffness-dependent, profibrotic activation of lung fibroblasts | Adiponectin suppresses stiffness-dependent, profibrotic activation of lung fibroblasts | DPLD | 10.1152/ajplung.00037.2024 | UGMLC | 2024 | Biosamples and Data | |
| An open-source framework for end-to-end analysis of electronic health record data. | An open-source framework for end-to-end analysis of electronic health record data. | DPLD | 10.1038/s41591-024-03214-0 | CPC-M | 2024 | Biosamples and Data | |
| Biofilm infections of endobronchial valves in COPD patients after endoscopic lung volume reduction: a pilot study with FISHseq | Biofilm infections of endobronchial valves in COPD patients after endoscopic lung volume reduction: a pilot study with FISHseq | COPD | 10.1038/s41598-024-73950-3 | BREATH | 2024 | Biosamples and Data | |
| Cluster-efficient pangenome graph construction with nf-core/pangenome. | Cluster-efficient pangenome graph construction with nf-core/pangenome. | DPLD | 10.1093/bioinformatics/btae609 | CPC-M | 2024 | Biosamples and Data | |
| Combination of calretinin, MALAT1, and GAS5 as a potential prognostic biomarker to predict disease progression in surgically treated mesothelioma patients | Combination of calretinin, MALAT1, and GAS5 as a potential prognostic biomarker to predict disease progression in surgically treated mesothelioma patients | LC | 10.1016/j.lungcan.2024.107802 | TLRC | 2024 | Biosamples and Data | |
| Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study | Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study | PALI | 10.1007/s15010-024-02292-z | BREATH | 2024 | Biosamples and Data | |
| COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors. | COPD basal cells are primed towards secretory to multiciliated cell imbalance driving increased resilience to environmental stressors. | DPLD | 10.1136/thorax-2022-219958 | CPC-M | 2024 | Biosamples and Data | |
| CT-guided needle biopsy is not associated with increased ipsilateral pleural metastasis | CT-guided needle biopsy is not associated with increased ipsilateral pleural metastasis | LC | 10.1016/j.lungcan.2024.107890 | TLRC | 2024 | Data | |
| CYFRA 21-1, CA 125 and CEA provide additional prognostic value in NSCLC patients with stable disease at first CT scan | CYFRA 21-1, CA 125 and CEA provide additional prognostic value in NSCLC patients with stable disease at first CT scan | LC | 10.3233/TUB-220042 | TLRC | 2024 | Data | |
| Data Management in Biobanking: Strategies, Challenges, and Future Directions. | Data Management in Biobanking: Strategies, Challenges, and Future Directions. | PLB | 10.3390/biotech13030034 | ARCN | 2024 | n.a. | |
| Dissecting AI-based mutation prediction in lung adenocarcinoma: A comprehensive real-world study | Dissecting AI-based mutation prediction in lung adenocarcinoma: A comprehensive real-world study | LC | 10.1016/j.ejca.2024.114292 | TLRC | 2024 | Data | |
| Effects of Repeated Freeze and Thaw Cycles on the Genome-Wide DNA Methylation Profile of Isolated Genomic DNA | Effects of Repeated Freeze and Thaw Cycles on the Genome-Wide DNA Methylation Profile of Isolated Genomic DNA | PLB | 10.1089/bio.2022.0045 | BREATH | 2024 | Biosamples and Data | |
| Expiratory Venous Volume and Arterial Tortuosity are Associated with Disease Severity and Mortality Risk in Patients with COPD: Results from COSYCONET. | Expiratory Venous Volume and Arterial Tortuosity are Associated with Disease Severity and Mortality Risk in Patients with COPD: Results from COSYCONET. | DPLD | 10.2147/COPD.S458905 | CPC-M | 2024 | Biosamples and Data | |
| Exploring secretory proteome and cytokine kinetic of human peripheral blood mononuclear cells exposed to methicillin-resistant Staphylococcus aureus biofilms and planktonic bacteria | Exploring secretory proteome and cytokine kinetic of human peripheral blood mononuclear cells exposed to methicillin-resistant Staphylococcus aureus biofilms and planktonic bacteria | PALI | 10.3389/fimmu.2024 | BREATH | 2024 | Biosamples and Data | |
| Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis. | Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis. | DPLD | 10.1172/jci.insight.168889 | UGMLC, CPC-M | 2024 | Biosamples and Data | |
| Fluorescent Techniques for RNA Detection in Nanoparticles. | Fluorescent Techniques for RNA Detection in Nanoparticles. | DPLD | 10.1007/978-1-0716-3918-4_14 | CPC-M | 2024 | Biosamples and Data | |
| Frequency and clinical significance of Herpes simplex virus type 1/2 reactivation in adult patients with mild to moderately severe community-acquired pneumonia: a multicentre cohort study | Frequency and clinical significance of Herpes simplex virus type 1/2 reactivation in adult patients with mild to moderately severe community-acquired pneumonia: a multicentre cohort study | PALI | 10.1007/s15010-024-02351-5 | BREATH | 2024 | Biosamples and Data | |
| GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension | GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension | PH | 10.1161/CIRCRESAHA.123.323736 | UGMLC | 2024 | Biosamples and Data | |
| Human Bronchial Epithelial Cell Transcriptome Changes in Response to Serum from Patients with Different Status of Inflammation. | Human Bronchial Epithelial Cell Transcriptome Changes in Response to Serum from Patients with Different Status of Inflammation. | PALI | 10.1007/s00408-024-00679-1 | BREATH | 2024 | Biosamples and Data | |
| IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota | IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota | PALI | 10.1073/pnas.2310864121 | BREATH | 2024 | Biosamples and Data | |
| Integration of Inventory Data from Cohort and Registry Studies into an Existing Research Network: National Pandemic Cohort Network (NAPKON) | Integration of Inventory Data from Cohort and Registry Studies into an Existing Research Network: National Pandemic Cohort Network (NAPKON) | PALI | 10.1055/a-2346-9680 | BREATH | 2024 | Data | |
| It takes two peroxisome proliferator-activated receptors (PPAR-β/δ and PPAR-γ) to tango idiopathic pulmonary fibrosis | It takes two peroxisome proliferator-activated receptors (PPAR-β/δ and PPAR-γ) to tango idiopathic pulmonary fibrosis | DPLD | 10.1186/s12931-024-02935-7 | UGMLC | 2024 | Biosamples and Data | |
| Low tumor interleukin-1beta expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study | Low tumor interleukin-1beta expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study | LC | 10.1016/j.pulmoe.2024.03.003 | TLRC | 2024 | Biosamples and Data | |
| OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data. | OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data. | DPLD | 10.1038/s41592-024-02197-7 | CPC-M | 2024 | Biosamples and Data | |
| Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication. | Oxysterole-binding protein targeted by SARS-CoV-2 viral proteins regulates coronavirus replication. | DPLD | 10.3389/fcimb.2024.1383917 | CPC-M | 2024 | Biosamples and Data | |
| Panpipes: a pipeline for multiomic single-cell and spatial transcriptomic data analysis. | Panpipes: a pipeline for multiomic single-cell and spatial transcriptomic data analysis. | DPLD | 10.1186/s13059-024-03322-7 | CPC-M | 2024 | Biosamples and Data | |
| Parallel detection of multiple biomarkers in a point-of-care-competent device for the prediction of exacerbations in chronic inflammatory lung disease | Parallel detection of multiple biomarkers in a point-of-care-competent device for the prediction of exacerbations in chronic inflammatory lung disease | AA, COPD | 10.1038/s41598-024-62784-8 | ARCN | 2024 | Biosamples and Data | |
| Peri- and postoperative morbidity and mortality in older patients with non-small cell lung cancer: a matched-pair study | Peri- and postoperative morbidity and mortality in older patients with non-small cell lung cancer: a matched-pair study | LC | 10.1186/s12957-024-03491-6 | TLRC | 2024 | Data | |
| Perioperative Predictive Factors for Tumor Regression and Survival in Non-Small Cell Lung Cancer Patients Undergoing Neoadjuvant Treatment and Lung Resection. | Perioperative Predictive Factors for Tumor Regression and Survival in Non-Small Cell Lung Cancer Patients Undergoing Neoadjuvant Treatment and Lung Resection. | DPLD | 10.3390/cancers16162885 | CPC-M | 2024 | Biosamples and Data | |
| Perip+A27:F36heral Inflammation Featuring Eosinophilia or Neutrophilia Is Associated with the Survival and Infiltration of Eosinophils within the Tumor among Various Histological Subgroups of Patients with NSCLC | Perip+A27:F36heral Inflammation Featuring Eosinophilia or Neutrophilia Is Associated with the Survival and Infiltration of Eosinophils within the Tumor among Various Histological Subgroups of Patients with NSCLC | LC | 10.3390/ijms25179552 | TLRC, UGMLC | 2024 | Data | |
| PITX2 as a Sensitive and Specific Marker of Midgut Neuroendocrine Tumors: Results from a Cohort of 1157 Primary Neuroendocrine Neoplasms | PITX2 as a Sensitive and Specific Marker of Midgut Neuroendocrine Tumors: Results from a Cohort of 1157 Primary Neuroendocrine Neoplasms | LC | 10.1016/j.modpat.2024.100442 | TLRC | 2024 | Data | |
| Population-Based Biobanking. | Population-Based Biobanking. | PLB | 10.3390/genes15010066 | ARCN | 2024 | n.a. | |
| Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis | Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis | DPLD | 10.1101/2024.04.24.589970 | UGMLC | 2024 | Biosamples and Data | |
| Prognostic value of tumor markers ProGRP, NSE and CYFRA 21-1 in patients with small cell lung cancer and chemotherapy-induced remission | Prognostic value of tumor markers ProGRP, NSE and CYFRA 21-1 in patients with small cell lung cancer and chemotherapy-induced remission | LC | 10.3233/TUB-230016 | TLRC | 2024 | Biosamples and Data | |
| Resurgence of common respiratory viruses in patients with community-acquired pneumonia (CAP)-A prospective multicenter study | Resurgence of common respiratory viruses in patients with community-acquired pneumonia (CAP)-A prospective multicenter study | PALI | 10.1016/j.jcv.2024.105694 | BREATH | 2024 | Biosamples and Data | |
| Robotic thoracic surgery for neurogenic tumors | Robotic thoracic surgery for neurogenic tumors | LC | 10.3171/2024.3.JNS232860 | TLRC | 2024 | Data | |
| Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts. | Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts. | DPLD | 10.1183/13993003.01326-2023 | CPC-M | 2024 | Biosamples and Data | |
| Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses | Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses | PALI | 10.1016/j.isci.2024.109330 | BREATH | 2024 | Biosamples and Data | |
| Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery. | Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery. | DPLD | 10.1007/164_2023_703 | CPC-M | 2024 | Biosamples and Data | |
| The diverging roles of insulin-like growth factor binding proteins in pulmonary arterial hypertension | The diverging roles of insulin-like growth factor binding proteins in pulmonary arterial hypertension | PH | 10.1016/j.vph.2024.107379 | UGMLC | 2024 | Biosamples and Data | |
| The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation | The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation | PALI | 10.1016/j.cell.2024.06.014 | BREATH | 2024 | Biosamples and Data | |
| The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer | The pregnancy-associated protein glycodelin as a potential sex-specific target for resistance to immunotherapy in non-small cell lung cancer | LC | 10.1016/j.trsl.2024.02.007 | ARCN, TLRC | 2024 | Biosamples and Data | |
| A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages | A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages | PALI | 10.1038/s41467-025-60084-x | UGMLC | 2025 | Biosamples and Data | |
| Assessing lung cancer progression and survival with infrared spectroscopy of blood serum. | Assessing lung cancer progression and survival with infrared spectroscopy of blood serum. | LC | 10.1186/s12916-025-03924-3 | CPC-M | 2025 | Biosamples and Data | |
| Association of the soluble form of the endothelial Tie2 receptor with organ failure and mortality in patients with sepsis and ARDS | Association of the soluble form of the endothelial Tie2 receptor with organ failure and mortality in patients with sepsis and ARDS | PALI | 10.1016/j.cyto.2025.157062 | BREATH | 2025 | Biosamples and Data | |
| Biases in machine-learning models of human single-cell data | Biases in machine-learning models of human single-cell data | DPLD | 10.1038/s41556-025-01619-8 | CPC-M CPC-M bioArchive | 2025 | n.a. | |
| BMB Nord: Dezentrale Infrastruktur zur standardisierten Erhebung und Bereitstellung von Spenderdaten und Bioproben für die pneumologische Forschung | BMB Nord: Dezentrale Infrastruktur zur standardisierten Erhebung und Bereitstellung von Spenderdaten und Bioproben für die pneumologische Forschung | PLB | ARCN | 2025 | Biosamples and Data | ||
| Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis. | Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis. | LC | 10.1186/s40170-025-00400-7 | TLRC | 2025 | Biosamples and Data | |
| Cholesterol Regulates Airway Epithelial Cell Differentiation by Inhibiting p53 Nuclear Translocation | Cholesterol Regulates Airway Epithelial Cell Differentiation by Inhibiting p53 Nuclear Translocation | DPLD | 10.3390/ijms26178324 | CPC-M | 2025 | Biosamples and Data | |
| Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies | Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies | DPLD | 10.1186/s12931-025-03132-w | CPC-M CPC-M bioArchive | 2025 | Biosamples and Data | |
| Collagen Post-Translational Modifications Are Altered in Idiopathic Pulmonary Fibrosis, Including within Extracellular Matrix Receptor Binding Motifs | Collagen Post-Translational Modifications Are Altered in Idiopathic Pulmonary Fibrosis, Including within Extracellular Matrix Receptor Binding Motifs | DPLD | 10.1164/rccm.202505-1276RL | CPC-M | 2025 | Biosamples and Data | |
| Community-acquired pneumonia in diabetic patients is characterized by a distinct pathogen spectrum and enhanced inflammation: results from CAPNETZ, a prospective observational cohort study | Community-acquired pneumonia in diabetic patients is characterized by a distinct pathogen spectrum and enhanced inflammation: results from CAPNETZ, a prospective observational cohort study | PALI | 10.1007/s15010-025-02659-w | BREATH | 2025 | Biosamples and Data | |
| Comparing viral, bacterial and co-infections in community-acquired pneumonia, a retrospective cohort study | Comparing viral, bacterial and co-infections in community-acquired pneumonia, a retrospective cohort study | PALI | 10.1016/j.ijid.2025.107841 | BREATH | 2025 | Biosamples and Data | |
| Considerations for building and using integrated single-cell atlases | Considerations for building and using integrated single-cell atlases | DPLD | 10.1038/s41592-024-02532-y | CPC-M CPC-M bioArchive | 2025 | n.a. | |
| Deep Learning-Based Short Text Summarization: An Integrated BERT and Transformer Encoder–Decoder Approach | Deep Learning-Based Short Text Summarization: An Integrated BERT and Transformer Encoder–Decoder Approach | PLB | 10.3390/computation13040096 | ARCN | 2025 | n.a. | |
| Deficiency of Smooth Muscle ADAR1 Exacerbates Vascular Remodeling and Pulmonary Hypertension. | Deficiency of Smooth Muscle ADAR1 Exacerbates Vascular Remodeling and Pulmonary Hypertension. | PH | 10.1161/CIRCRESAHA.125.326235 | UGMLC | 2025 | Biosamples and Data | |
| Demographics and outcome of Legionella pneumonia in the intensive care unit: a retrospective multicenter cohort study | Demographics and outcome of Legionella pneumonia in the intensive care unit: a retrospective multicenter cohort study | PALI | 10.1186/s13054-025-05524-2 | BREATH | 2025 | Data | |
| Development of a Polidocanol-based Human In Vitro Model to Explore Airway Epithelial Repair | Development of a Polidocanol-based Human In Vitro Model to Explore Airway Epithelial Repair | DPLD | 10.1165/rcmb.2024-0117OC | CPC-M | 2025 | Biosamples and Data | |
| Differential Effects of Antifibrotic Treatment on Outcome Prediction via Serial Matrix Metalloproteinase-Degraded C-Reactive Protein Neoepitope Levels in Idiopathic Pulmonary Fibrosis | Differential Effects of Antifibrotic Treatment on Outcome Prediction via Serial Matrix Metalloproteinase-Degraded C-Reactive Protein Neoepitope Levels in Idiopathic Pulmonary Fibrosis | DPLD | 10.1016/j.chest.2025.08.047 | BREATH | 2025 | Biosamples and Data | |
| Differential expression of eicosanoid pathways after whole blood stimulation in asthma patients. | Differential expression of eicosanoid pathways after whole blood stimulation in asthma patients. | AA | 10.1016/j.waojou.2025.101047 | ARCN | 2025 | Biosamples and Data | |
| Dual Impacts of Lung Transplantation on the Recovery and Comorbidity of Interstitial Lung Diseases: A Longitudinal Assessment of the Benefits and Burden | Dual Impacts of Lung Transplantation on the Recovery and Comorbidity of Interstitial Lung Diseases: A Longitudinal Assessment of the Benefits and Burden | DPLD | 10.3390/jcm14186420 | UGMLC | 2025 | Data | |
| Dynamics of contact behaviour by self-reported COVID-19 vaccination and infection status during the COVID-19 pandemic in Germany: an analysis of two large population-based studies. | Dynamics of contact behaviour by self-reported COVID-19 vaccination and infection status during the COVID-19 pandemic in Germany: an analysis of two large population-based studies. | PALI | 10.1186/s12916-025-04211-x | BREATH | 2025 | Biosamples and Data | |
| Endothelin-1 in combination with CRB-65 enhance risk stratification in COVID-19 patients. | Endothelin-1 in combination with CRB-65 enhance risk stratification in COVID-19 patients. | PALI | 10.1007/s15010-025-02627-4 | BREATH | 2025 | Biosamples and Data | |
| Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures | Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures | LC | 10.1016/j.molcel.2024.11.014 | TLRC | 2025 | Biosamples and Data | |
| European ILD registry algorithm for self-assessment in interstitial lung diseases (eurILDreg ASA-ILD). | European ILD registry algorithm for self-assessment in interstitial lung diseases (eurILDreg ASA-ILD). | DPLD | 10.1371/journal.pone.0316484 | UGMLC | 2025 | Data | |
| Exploring trends and predictors of long-term asthma remission | Exploring trends and predictors of long-term asthma remission | AA | 10.1016/j.waojou.2025.101127 | ARCN | 2025 | Biosamples and Data | |
| First-line nivolumab plus ipilimumab in pleural mesothelioma: Efficacy and safety data from the real-world MesoNet study | First-line nivolumab plus ipilimumab in pleural mesothelioma: Efficacy and safety data from the real-world MesoNet study | LC | 10.1016/j.lungcan.2025.108702 | ARCN | 2025 | Data | |
| Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany. | Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany. | PALI | 10.1038/s41598-025-00945-z | BREATH | 2025 | Biosamples and Data | |
| High GLUT1 protein expression is associated with unfavorable tumor features and poor prognosis in non-small cell lung cancer | High GLUT1 protein expression is associated with unfavorable tumor features and poor prognosis in non-small cell lung cancer | LC | 10.21037/tlcr-2025-422 | ARCN | 2025 | Biosamples and Data | |
| Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease | Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease | ROR, CFBE | 10.1186/s13287-025-04737-0 | BREATH | 2025 | Biosamples and Data | |
| Identification of a novel RSPO1-NUMT insertion in a LUAD patient cohort and the challenges and insights into NUMT detection highlighting the importance of reference genomes and population databases. | Identification of a novel RSPO1-NUMT insertion in a LUAD patient cohort and the challenges and insights into NUMT detection highlighting the importance of reference genomes and population databases. | LC | 10.21037/tlcr-2025-586 | TLRC | 2025 | Biosamples and Data | |
| Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations | Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations | AA | 10.1111/all.70070 | ARCN | 2025 | Biosamples and Data | |
| Impact of the number of involved lymph node zones on survival in stage IIIA-N2 lung adeno and squamous cell carcinoma. | Impact of the number of involved lymph node zones on survival in stage IIIA-N2 lung adeno and squamous cell carcinoma. | LC | 10.1093/icvts/ivaf121 | TLRC | 2025 | Data | |
| Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy | Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy | LC | 10.1016/j.stem.2025.01.002 | TLRC | 2025 | Biosamples | |
| Intratumor Heterogeneity Predicts Prognosis in Lepidic Predominant Lung Adenocarcinoma | Intratumor Heterogeneity Predicts Prognosis in Lepidic Predominant Lung Adenocarcinoma | LC | 10.1111/1759-7714.15536 | TLRC | 2025 | Data | |
| Living human lung slices for ex vivo modelling of lung cancer. | Living human lung slices for ex vivo modelling of lung cancer. | LC | 10.1172/jci.insight.190703 | TLRC, UGMLC | 2025 | Biosamples and Data | |
| Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study | Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study | AA | 10.1016/j.jacig.2025.100533 | BREATH | 2025 | Data | |
| Loss of pulmonary capillaries in idiopathic pulmonary arterial hypertension with low diffusion capacity is accompanied by early diffuse emphysema detected by 129Xe MRI | Loss of pulmonary capillaries in idiopathic pulmonary arterial hypertension with low diffusion capacity is accompanied by early diffuse emphysema detected by 129Xe MRI | PH | 10.1007/s00330-024-11209-1 | BREATH | 2025 | Data | |
| Low tumour interleukin-1β expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study. | Low tumour interleukin-1β expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study. | LC | 10.1080/25310429.2024.2447637 | TLRC | 2025 | Biosamples and Data | |
| Low-coverage whole genome sequencing of cell-free DNA to predict and track immunotherapy response in advanced non-small cell lung cancer | Low-coverage whole genome sequencing of cell-free DNA to predict and track immunotherapy response in advanced non-small cell lung cancer | LC | 10.1186/s13046-025-03348-0 | TLRC | 2025 | Biosamples and Data | |
| LTI-03 peptide demonstrates anti-fibrotic activity in ex vivo lung slices from patients with IPF. | LTI-03 peptide demonstrates anti-fibrotic activity in ex vivo lung slices from patients with IPF. | DPLD | 10.1016/j.isci.2025.113437 | UGMLC | 2025 | Biosamples | |
| Maternal Smoking and CC-16: Implications for Lung Development and COPD Across the Lifespan | Maternal Smoking and CC-16: Implications for Lung Development and COPD Across the Lifespan | AA | 10.1164/rccm.202504-0854OC | ARCN | 2025 | Biosamples and Data | |
| Nebulization of RNA-Loaded Micelle-Embedded Polyplexes as a Potential Treatment of Idiopathic Pulmonary Fibrosis | Nebulization of RNA-Loaded Micelle-Embedded Polyplexes as a Potential Treatment of Idiopathic Pulmonary Fibrosis | DPLD | 10.1021/acsami.4c21657 | CPC-M CPC-M bioArchive | 2025 | Biosamples and Data | |
| Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: results of the NEOMUN trial. | Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: results of the NEOMUN trial. | LC | 10.1136/jitc-2025-011874 | TLRC, UGMLC | 2025 | Biosamples and Data | |
| NeoTRACK trial: Neo adjuvant T i R agolumab, A tezolizumab and C hemotherapy - dissection of IO- efficacy in NSCLC by longitudinal trac K ing - protocol of a non-randomised, open-label, single-arm, phase II study | NeoTRACK trial: Neo adjuvant T i R agolumab, A tezolizumab and C hemotherapy - dissection of IO- efficacy in NSCLC by longitudinal trac K ing - protocol of a non-randomised, open-label, single-arm, phase II study | LC | 10.1136/bmjopen-2024-096617 | TLRC | 2025 | Biosamples and Data | |
| Occurrence and clinical correlates of SARS-CoV-2 viremia in two German patient cohorts | Occurrence and clinical correlates of SARS-CoV-2 viremia in two German patient cohorts | PALI | 10.1080/22221751.2025.2459137 | BREATH | 2025 | Biosamples and Data | |
| Outcomes of central versus peripheral arterial cannulation for intraoperative extracorporeal membrane oxygenation support in lung transplantation | Outcomes of central versus peripheral arterial cannulation for intraoperative extracorporeal membrane oxygenation support in lung transplantation | ROR, CFBE | 10.1016/j.healun.2025.09.025 | BREATH | 2025 | Data | |
| Pathogen identification and outcome in adult patients with community-acquired pneumonia in Switzerland: findings from the Swiss CAPNETZ cohort study | Pathogen identification and outcome in adult patients with community-acquired pneumonia in Switzerland: findings from the Swiss CAPNETZ cohort study | PALI | 10.1007/s15010-025-02699-2 | BREATH | 2025 | Biosamples and Data | |
| Pathogenic SMAD6 variants in patients with idiopathic and complex congenital heart disease associated pulmonary arterial hypertension | Pathogenic SMAD6 variants in patients with idiopathic and complex congenital heart disease associated pulmonary arterial hypertension | PH | 10.1038/s41525-025-00484-6 | BREATH | 2025 | Biosamples and Data | |
| Performance of risk prediction scores for severe pneumonia in patients with community-acquired pneumonia after organ transplantation. | Performance of risk prediction scores for severe pneumonia in patients with community-acquired pneumonia after organ transplantation. | PALI | 10.1183/23120541.00212-2025 | BREATH | 2025 | Data | |
| Photon-counting Computed Tomography in a Patient with Pulmonary Veno-Occlusive Disease | Photon-counting Computed Tomography in a Patient with Pulmonary Veno-Occlusive Disease | PH | 10.1164/rccm.202411-2184IM | BREATH | 2025 | Data | |
| Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma. | Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma. | LC | 10.1002/ijc.70231 | TLRC, UGMLC | 2025 | Biosamples and Data | |
| Prognostic impact of lepidic growth in intermediate and high-grade lung adenocarcinoma. | Prognostic impact of lepidic growth in intermediate and high-grade lung adenocarcinoma. | LC | 10.1016/j.lungcan.2025.108674 | TLRC | 2025 | Data | |
| Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections. | Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections. | PALI | 10.1038/s41598-025-85229-2 | BREATH | 2025 | Biosamples and Data | |
| Protocol and research program of the European registry and biobank for interstitial lung diseases (eurILDreg) | Protocol and research program of the European registry and biobank for interstitial lung diseases (eurILDreg) | DPLD | 10.1186/s12890-024-03389-9 | UGMLC | 2025 | n.a. | |
| Pulmonary Hypertension Drives Prognosis in Idiopathic Pulmonary Fibrosis: Insights from the European IPF Registry. | Pulmonary Hypertension Drives Prognosis in Idiopathic Pulmonary Fibrosis: Insights from the European IPF Registry. | PH, DPLD | 10.3390/jcm14207352 | UGMLC | 2025 | Data | |
| Randomizedadaptive assessment of post COVID syndrome treatments (RAPID): a study protocolfor a multicenter, randomized, controlled adaptive platform trial of treatmentoptions for Post Covid Syndrome (PCS) on patients physical function includingthe first intervention specific appendix RAPID_REVIVE (reducing inflammatoryactivity in patients with PCS). | Randomizedadaptive assessment of post COVID syndrome treatments (RAPID): a study protocolfor a multicenter, randomized, controlled adaptive platform trial of treatmentoptions for Post Covid Syndrome (PCS) on patients physical function includingthe first intervention specific appendix RAPID_REVIVE (reducing inflammatoryactivity in patients with PCS). | PALI | 10.1186/s12889-025-24865-9 | BREATH | 2025 | Biosamples and Data | |
| Rationale and design of the Pneumococcal Pneumonia Epidemiology, Urine Serotyping and Mental Outcomes (PNEUMO) study Europe. | Rationale and design of the Pneumococcal Pneumonia Epidemiology, Urine Serotyping and Mental Outcomes (PNEUMO) study Europe. | PALI | 10.1183/23120541.00237-2025 | BREATH | 2025 | Biosamples and Data | |
| Reduced Claudin-3 expression is linked to unfavorable tumor features and poor prognosis in non-small cell lung cancer | Reduced Claudin-3 expression is linked to unfavorable tumor features and poor prognosis in non-small cell lung cancer | LC | 10.2147/LCTT.S530791 | ARCN | 2025 | Biosamples and Data | |
| RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. | RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. | LC | 10.1038/s41467-025-60223-4 | TLRC, UGMLC | 2025 | Biosamples | |
| Robot-Assisted Versus Open Surgery for the Resection of Large Thymomas: A Retrospective Cohort Study. | Robot-Assisted Versus Open Surgery for the Resection of Large Thymomas: A Retrospective Cohort Study. | LC | 10.1002/jso.28113 | TLRC | 2025 | Data | |
| scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome | scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome | AA | 10.1038/s41467-025-64778-0 | ARCN | 2025 | Biosamples and Data | |
| Self-organizing map clustering identifies high-risk clusters of post-acute mortality in a prospective multicenter study of community-acquired pneumonia | Self-organizing map clustering identifies high-risk clusters of post-acute mortality in a prospective multicenter study of community-acquired pneumonia | PALI | 10.1183/23120541.00374-2025 | BREATH | 2025 | Biosamples and Data | |
| Serotype distribution and coverage by pneumococcal vaccines in hospitalized adults with pneumococcal pneumonia in Germany | Serotype distribution and coverage by pneumococcal vaccines in hospitalized adults with pneumococcal pneumonia in Germany | PALI | 10.1183/23120541.00946-2025 | BREATH | 2025 | Biosamples and Data | |
| Serratia sp. traits distinguish the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases | Serratia sp. traits distinguish the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases | TB | 10.1371/journal.pone.0325362 | ARCN | 2025 | Biosamples and Data | |
| Serum levels of C-terminal peptides of alpha-1 antitrypsin as potential biomarkers in non-small cell lung cancer. | Serum levels of C-terminal peptides of alpha-1 antitrypsin as potential biomarkers in non-small cell lung cancer. | LC | 10.21037/tlcr-2025-178 | BREATH, TLRC | 2025 | Biosamples and Data | |
| Shotgun Lipidomics Analyse von PBMCs – Einfluss der Temperatur bei 24-stündiger Lagerung im Vergleich zur Direktverarbeitung | Shotgun Lipidomics Analyse von PBMCs – Einfluss der Temperatur bei 24-stündiger Lagerung im Vergleich zur Direktverarbeitung | PLB | ARCN | 2025 | Biosamples and Data | ||
| SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism | SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism | LC | 10.1002/ijc.35202 | TLRC, UGMLC | 2025 | Biosamples and Data | |
| Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination | Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination | PALI | 10.1038/s43587-025-00819-z | BREATH | 2025 | Biosamples and Data | |
| SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC. | SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC. | LC | 10.1038/s41416-025-02970-1 | ARCN, CPC-M,TLRC | 2025 | Biosamples and Data | |
| Spatial single-cell atlas reveals regional variations in healthy and diseased human lung | Spatial single-cell atlas reveals regional variations in healthy and diseased human lung | LC, COPD | 10.1038/s41467-025-65704-0 | CPC-M | 2025 | Biosamples and Data | |
| Surface proteome of plasma extracellular vesicles differentiates between SARS-CoV-2 and Influenza infection | Surface proteome of plasma extracellular vesicles differentiates between SARS-CoV-2 and Influenza infection | PALI | 10.1080/21505594.2025.2590305 | BREATH | 2025 | Biosamples and Data | |
| T cells of patients with systemic sclerosis or Sjögren's disease display an aberrant metabolic state and memory phenotype in blood and lungs | T cells of patients with systemic sclerosis or Sjögren's disease display an aberrant metabolic state and memory phenotype in blood and lungs | DPLD | 10.1093/rheumatology/keaf198 | BREATH | 2025 | Biosamples and Data | |
| Targeting pleuro-alveolar junctions reverses lung fibrosis in mice | Targeting pleuro-alveolar junctions reverses lung fibrosis in mice | DPLD | 10.1038/s41467-024-55596-x | CPC-M CPC-M bioArchive | 2025 | Biosamples and Data | |
| Withdrawal of prostacyclin pathway therapies after initiation of sotatercept treatment in patients with pulmonary arterial hypertension | Withdrawal of prostacyclin pathway therapies after initiation of sotatercept treatment in patients with pulmonary arterial hypertension | PH | 10.1183/13993003.00064-2025 | BREATH | 2025 | Data | |
| Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension | Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension | PH | 10.1164/rccm.202409-1763OC | UGMLC | 2025 | Biosamples and Data |
| wdt_ID | Abkürzung | Bedeutung | ID |
|---|---|---|---|
| 2 | Work Type | 1 | |
| 4 | Original | Originalarbeiten mit Peer Review (z. B. Research Paper, Meta-Analyse, Short Communication, Research Letter, Guideline) | |
| 6 | Review | Originalarbeiten mit begrenztem Peer Review | |
| 8 | Other | Sonstige Publikationen ohne Peer Review (z. B. Letter to the Editor, Reply, Response, Editorial) | |
| 10 | Involved site partner(s) | 1 | |
| 12 | CAU | Christian-Albrechts-Universität zu Kiel | |
| 14 | UzL | Universität zu Lübeck | |
| 16 | FZB | Forschungszentrum Borstel | |
| 18 | Ghd | LungenClinic Großhansdorf | |
| 20 | MHH | Medizinische Hochschule Hannover (Hannover Medical School) | |
| 22 | LUH | Leibniz Universität Hannover | |
| 24 | ITEM | Fraunhofer-Institut für Toxikologie und Experimentelle Medizin in Hannover | |
| 26 | JLU | Justus-Liebig-Universität Gießen | |
| 28 | UMR | Philipps-Universität Marburg | |
| 30 | MPI-BN | Max-Planck-Institut für Herz- und Lungenforschung in Bad Nauheim | |
| 32 | UKHD | Universitätsklinikum Heidelberg | |
| 34 | RKU | Ruprecht-Karls-Universität Heidelberg | |
| 36 | Thorax | Thoraxklinik am Universitätsklinikum Heidelberg | |
| 38 | DKFZ | Deutsches Krebsforschungszentrum | |
| 40 | EMBL | European Molecular Biology Laboratory | |
| 42 | HMGU | Helmholtz Zentrum München – Deutsches Forschungszentrum für Gesundheit und Umwelt | |
| 44 | LMU | Ludwig-Maximilians-Universität München | |
| 46 | KUM | Klinikum der Universität München | |
| 48 | Assoziierte Partner | 1 | |
| 50 | ASK | Asklepios Fachkliniken München-Gauting | |
| 52 | CAPNETZ | CAPNETZ Stiftung | |
| 54 | COSYCONET | German COPD and Systemic Consequences – Comorbidities Network | |
| 56 | NAKO | Nationale Kohorte e. V. | |
| 58 | PRI | Pneumologisches Forschungsinstitut an der LungenClinic Grosshansdorf GmbH | |
| 60 | PROGNOSIS | The Prospective German Non-CF-Bronchiectasis Registry | |
| 62 | PROGRESS | Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Sepsis | |
| 64 | RKI | Robert Koch-Institut | |
| 66 | UKSH (Kiel) | Universitätsklinikum Schleswig-Holstein – Campus Kiel | |
| 68 | UKSH (Lübeck) | Universitätsklinikum Schleswig-Holstein – Campus Lübeck | |
| 70 | BIH | Berliner Institut für Gesundheitsforschung (Berlin Institut of Health) | |
| 72 | Involved DZL site(s) | 1 | |
| 74 | Assoziierter Partner | ||
| 76 | ARCN | Airway Research Center North | |
| 78 | BREATH | Biomedical Research in Endstage and Obstructive Lung Disease Hanover | |
| 80 | CPC-M | Comprehensive Pneumology Center Munich | |
| 82 | TLRC | Translational Lung Research Center Heidelberg | |
| 84 | UGMLC | Universities of Giessen and Marburg Lung Center | |
| 86 | Disease Area(s) | 1 | |
| 88 | AA | Asthma and Allergy | |
| 92 | CFBE | Cystische Fibrose & Bronchiektaseerkrankungen | |
| 94 | COPD | Chronic Obstructive Pulmonary Disease | |
| 96 | DPLD | Diffuse Parenchymal Lung Disease | |
| 100 | General Lung and Other | (Allgemeine Themen wie z. B. Raucherentwöhnung etc.) | |
| 102 | LC | Lung Cancer | |
| 104 | PH | Pulmonary Hypertension | |
| 106 | PLB | Biobanking and Data Management Platform | |
| 108 | PLI | Imaging Platform | |
| 110 | PALI | Pneumonia & Acute Lung Injury | |
| 111 | ROR | Regeneration & Organ Replacement |
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