PURPOSE: To investigate the association of vertebral CT attenuation between virtual non-contrast (VNC) and true non-contrast (TNC) images and to evaluate if VNC vertebral CT attenuation could be used for phantom-less osteoporosis detection in dual-layer spectral-detector CT (SDCT). METHODS: 200 patients with non-contrast and portal-venous phase SDCT were retrospectively assigned to a test and a validation group of 100 patients each. CT attenuation of L1 vertebrae were measured on VNC and TNC. The test group was used to determine the difference between VNC and TNC CT attenuation and to calculate a statistical model for TNC CT attenuation prediction. The validation group was used to assess the capability of the model to predict TNC from VNC CT attenuation and its accuracy to identify osteoporosis. Osteoporosis was defined as a TNC CT attenuation of
Ding, Y.
Richter, A.
Stiller, W.
Kauczor, H. U.
Weber, T. F.
Keywords
- Aged
- Female
- Humans
- Male
- Middle Aged
- Osteoporosis/*diagnostic imaging
- Reproducibility of Results
- Retrospective Studies
- Spine/diagnostic imaging
- Tomography, X-Ray Computed/*instrumentation/*methods
- Bone mineral density
- Computed tomography
- Dual-energy CT
- Osteoporosis
- Virtual non-contrast images
