PURPOSE: To implement and test variants of chemical shift imaging (CSI) acquiring both free induction decays (FIDs) showing all dissolved-phase compartments and spin echoes for specifically assessing 129 Xe in lipids in order to perform precise lipid-dissolved 129 Xe MR thermometry in a rat model of general hypothermia. METHODS: Imaging was performed at 2.89 T. T2 of 129 Xe in lipids was determined in one rat by fitting exponentials to decaying signals of global spin-echo spectra. Four rats (conventional CSI) and six rats (turbo spectroscopic imaging) were scanned at three time points with core body temperature 37/34/37
- Kern, A. L.
- Gutberlet, M.
- Rumpel, R.
- Bruesch, I.
- Hohlfeld, J. M.
- Wacker, F.
- Hensen, B.
Keywords
- 129 $$ {}^{129} $$ Xe
- MRI thermometry
- chemical-shift imaging
- lipid
- rat
- spin echo
