Science and Research

The ATP-mediated cytokine release by macrophages is down-modulated by unconventional

OBJECTIVE: The clinical interest in mechanisms controlling the biosynthesis and release of the pro-inflammatory cytokine interleukin (IL)-1

  • Wolf, P. M. K.
  • Hanke, D.
  • Singh, V. K.
  • Keller, H. L.
  • Ettischer, L. J.
  • Teppe, L.
  • Amati, A. L.
  • Hecker, A.
  • Husain-Syed, F.
  • Rohde, M.
  • Nuber, U. A.
  • Büttner, K.
  • McIntosh, J. M.
  • Liese, J.
  • Mazurek, S.
  • Grau, V.
  • Richter, K.

Keywords

  • Humans
  • *Receptors, Nicotinic/metabolism/genetics/immunology
  • *Adenosine Triphosphate/metabolism
  • *Macrophages/metabolism/immunology
  • *Cytokines/metabolism
  • Interleukin-1beta/metabolism
  • THP-1 Cells
  • Down-Regulation
  • alpha7 Nicotinic Acetylcholine Receptor
  • inflammation
  • interleukin-1β
  • macrophages
  • monocytes
  • nicotinic acetylcholine receptors
  • non-neuronal cholinergic system
Publication details
DOI: 10.3389/fimmu.2025.1661114
Journal: Front Immunol
Pages: 1661114 
Work Type: Original
Location: UGMLC
Disease Area: PALI
Partner / Member: JLU
Access-Number: 41221292


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