Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.

• Hanuna, M.
• Pattathu, J.
• Buech, J.
• Kamla, C.
• Kneidinger, N.
• Behr, J.
• Milger, K.
• Veit, T.
• Nagel, M.
• Abicht, J.
• Dalla-Pozza, R.
• Fischer, M.
• Jakob, A.
• Hermann, M.
• Schramm, R.
• Rosenthal, L. L.
• Haas, N.
• Hörer, J.
• Hagl, C.
• Michel, S. G.