Science and Research

Association Between Subsegmental Dosing Accuracy and Outcomes of Bronchoscopic Thermal Vapor Ablation: An Exploratory Retrospective Study in Severe Heterogeneous Emphysema

PURPOSE: Bronchoscopic thermal vapor ablation (BTVA) is a minimally invasive treatment for severe emphysema. However, the treatment doses are typically generated at the segmental level. In specific cases, treatment needs to be conducted at the subsegmental level, and the proportion can only be roughly allocated based on CT image review, potentially leading to dose mismatch. This retrospective exploratory study investigated the relationship between subsegmental dose accuracy (theoretical-to-actual matching) and clinical outcomes following BTVA. METHODS: Patients who underwent BTVA at the Shanghai Chest Hospital between 2023 and 2024 were analyzed. Subsegmental theoretical doses (BroncQCT software) were compared to previously administered actual treatment doses. Dose matching was defined as: 1) segmental treatments were presumed matched (uniform vapor assumption), 2) subsegmental treatments required

  • Yang, H.
  • Chen, S.
  • Zheng, X.
  • Cui, N.
  • Xie, F.
  • Hou, H.
  • Ye, L.
  • Herth, F. J. F.
  • Sun, J.

Keywords

  • Humans
  • Retrospective Studies
  • Male
  • *Pulmonary Emphysema/physiopathology/surgery/diagnostic imaging/diagnosis
  • Female
  • Treatment Outcome
  • Middle Aged
  • Aged
  • *Bronchoscopy/adverse effects/methods
  • Severity of Illness Index
  • Time Factors
  • *Lung/physiopathology/surgery/diagnostic imaging
  • *Ablation Techniques/adverse effects
  • Forced Expiratory Volume
  • China
  • Tomography, X-Ray Computed
  • Recovery of Function
  • Blvr
  • Btva
  • Copd
  • bronchoscopic lung volume reduction
  • bronchoscopic thermal vapor ablation
  • chronic obstructive pulmonary disease
  • emphysema
Publication details
DOI: 10.2147/copd.S560457
Journal: Int J Chron Obstruct Pulmon Dis
Pages: 560457 
Work Type: Original
Location: TLRC
Disease Area: COPD
Partner / Member: Thorax
Access-Number: 41878299


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