Association of Obesity with Symptoms and Quality of Life in COPD: Results from COSYCONET

BACKGROUND: Body weight plays an intricate role in COPD, as obesity can impair lung function and thus might affect COPD categorization. We asked to which extent overweight/obesity affects conventional COPD scores taking into account lung function and potential restrictive patterns (PRISm, preserved ratio and impaired spirometry). METHODS: Patients of the COSYCONET cohort were included. Outcomes were the modified Medical Research Council (mMRC) questionnaire, the COPD Assessment Test (CAT), CAT question #4 (dyspnea upon exertion), the St George's Respiratory Questionnaire (SGRQ) and its domains, and the EQ-5D-VAS (EuroQoL-5-dimension) questionnaire for generic quality of life. Body mass index (BMI) was categorized into <25,

• Alter, P.
• Watz, H.
• Machado, F. V. C.
• Speicher, T.
• Trudzinski, F. C.
• Kahnert, K.
• Bals, R.
• Wouters, E. F. M.
• Franssen, F. M. E.
• Vogelmeier, C. F.
• Karrasch, S.
• Jörres, R. A.