Science and Research

COPD as a risk factor of the complications in lower limb arthroplasty: a patient-matched study

Purpose: A relevant proportion of patients undergoing joint replacement surgery for the treatment of osteoarthritis exhibit COPD. This coincidence may result from an increased prevalence of both the diseases in elderly patients. In this study, COPD, which is known to be associated with a variety of comorbidities, and its potential interactions, eg, mediated via systemic inflammation, are discussed. The purpose of the present study was to identify the role of COPD as an independent risk factor for complications after total knee and hip arthroplasty. Patients and methods: In a monocentric patient cohort of 2,760 arthoplasties, propensity score matching was done using the following factors: sex, age, replaced joint, American Society of Anesthesiologists' score, body mass index, hypertension, chronic heart disease, anticoagulation, diabetes mellitus, chronic renal deficiency, and actual smoking status to create 224 pairs. Both the pre-matched differences and the results after propensity score matching were statistically analyzed with p
  • Klasan, A.
  • Dworschak, P.
  • Heyse, T. J.
  • Ruchholtz, S.
  • Alter, P.
  • Vogelmeier, C. F.
  • Schwarz, P.
  • Keywords

    • *copd
    • *arthroplasty
    • *comorbidity
    • *complication
    • *pneumonia
    • *transfusion
    Publication details
    DOI: 10.2147/COPD.S161577
    Journal: International journal of chronic obstructive pulmonary disease
    Pages: 2495-2499 
    Work Type: Original
    Location: UGMLC
    Disease Area: COPD
    Partner / Member: UMR
    Access-Number: 30174419
    See publication on PubMed

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