Science and Research

Optimized culture of primary human alveolar type II cell-derived 3D organoids from fibrotic lung tissue with phenotypic and metabolic profiling

  • Schroder, L. J.
  • Ruckoldt, J.
  • Schubert, S.
  • Knudsen, L.
  • Janciauskiene, S. M.
  • Werlein, C.
  • Knoll, M.
  • Engelhardt, R.
  • Petzold-Mugge, C.
  • Schupp, J. C.
  • Hoeper, M. M.
  • Gottlieb, J.
  • Ius, F.
  • Zardo, P.
  • Lindenberg, M.
  • Riehle, C.
  • Neubert, L.
  • Kamp, J. C.

Keywords

  • Alveolar type II cells
  • Alveolosphere
  • Fibrotic end-stage
  • Human lung explant
  • Idiopathic pulmonary fibrosis
  • Lung epithelium
  • Lung organoids
Publication details
DOI: 10.1186/s12931-026-03610-9
Journal: Respir Res
Work Type: Original
Location: BREATH
Disease Area: PH
Partner / Member: MHH
Access-Number: 41792753
See publication on PubMed


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