BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung epithelial phenotypes, fibroblast activation, and increased extracellular matrix deposition. Transforming growth factor-beta (TGF-
- Boateng, E.
- Bonilla-Martinez, R.
- Ahlemeyer, B.
- Garikapati, V.
- Alam, M. R.
- Trompak, O.
- Oruqaj, G.
- El-Merhie, N.
- Seimetz, M.
- Ruppert, C.
- Günther, A.
- Spengler, B.
- Karnati, S.
- Baumgart-Vogt, E.
Keywords
- Humans
- *Idiopathic Pulmonary Fibrosis/metabolism/pathology/genetics
- *PPAR gamma/metabolism/genetics
- *PPAR-beta/metabolism/genetics/agonists
- Cells, Cultured
- *PPAR delta/metabolism/genetics
- Fibroblasts/metabolism/pathology/drug effects
- Peroxisomes/metabolism/drug effects
- Peroxisome Proliferator-Activated Receptors/metabolism
- Male
- Transforming Growth Factor beta1/metabolism
- Female
- Catalase
- Collagen
- Human lung fibroblasts
- Idiopathic pulmonary fibrosis
- Matrix metalloproteinases
- Pex13
- Ppar
- Peroxisome
- Tgf-β1
