Clonal hematopoiesis-related mutations associate with rapid IPF progression and lung function decline. Exploring them mechanistically may identify important diagnostic or therapeutic targets for IPF patients.
- Asarian, L.
- Jia, J.
- Sirokha, D.
- Paulini, L.
- Dietel, D.
- Stoleriu, M. G.
- Frankenberger, M.
- Yildirim, A. O.
- Gotze, K. S.
- Behr, J.
- Hunninghake, G. M.
- Fernandez, I. E.
Keywords
- Humans
- *Idiopathic Pulmonary Fibrosis/genetics/pathology/physiopathology
- *Clonal Hematopoiesis/genetics
- Disease Progression
- Mutation
- Lung/pathology/physiopathology
- Aging
- Biomarkers
- Fibrosis
- Genetic risk factors
- Pulmonology
