Science and Research

Phase-resolved Functional Lung MRI Reveals Distinct Lung Perfusion Phenotype in Children and Adolescents with Post-COVID-19 Condition

Background Although measurable organic dysfunctions are frequently absent in pediatric patients with post-COVID-19 condition (PCC), this condition adversely affects quality of life. Free-breathing phase-resolved functional lung (PREFUL) MRI may be useful for assessing lung function in pediatric patients with PCC. Purpose To detect lung changes in children and adolescents with PCC compared with healthy control participants using PREFUL MRI. Materials and Methods In this single-center, prospective, cross-sectional study conducted between April 2022 and April 2023, children and adolescents (age

  • Pöhler, G. H.
  • Voskrebenzev, A.
  • Heinze, M. L.
  • Skeries, V.
  • Klime
  • Glandorf, J.
  • Eckstein, J.
  • Babazade, N.
  • Wernz, M.
  • Pfeil, A.
  • Hansen, G.
  • Wacker, F. K.
  • Vogel-Claussen, J.
  • Wetzke, M.
  • Renz, D. M.

Keywords

  • Humans
  • Male
  • *COVID-19/diagnostic imaging/complications/physiopathology
  • Female
  • Adolescent
  • Child
  • Cross-Sectional Studies
  • Prospective Studies
  • *Magnetic Resonance Imaging/methods
  • *Lung/diagnostic imaging/physiopathology
  • *SARS-CoV-2
  • Phenotype
  • Ventilation-Perfusion Ratio
Publication details
DOI: 10.1148/radiol.241596
Journal: Radiology
Pages: e241596 
Number: 2
Work Type: Original
Location: BREATH
Disease Area: PLI, PALI
Partner / Member: MHH
Access-Number: 39998374

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