[Recurrent non-Hodgkin lymphoma of various subtypes and localizations of manifestation - case report of a recognized occupational disease caused by ionizing radiation]

A 77-year-old former MTA had been exposed to ionizing radiation for several years, e.g. during X-ray fluoroscopy and mouth pipetting of radioactive isotopes. There was no family history of lymphoma risk. She reported reduced performance, dizziness and mental stress.Imaging (MRI, PET-CT) and histology showed multiple B-cell NHL of different subtypes. Pulmonary function was slightly impaired; laboratory showed mild anemia.Recurrent non-Hodgkin's lymphoma (B-cell series), recognized as an occupational disease due to ionizing radiation (OD No. 2402 ODO).Treatments included radiotherapy, immunochemotherapies, CAR T-cell therapy, Nivolumab and Ibrutinib. Despite multiple remissions, cutaneous recurrences occurred. Currently remission under Ibrutinib.Physicians (in the following, this refers to all genders) should take a work history and, if there is reasonable suspicion, they are legally obliged to report suspected occupational diseases (which is more important than confidentiality). Occupational safety, including radiation protection, must be optimized in order to avoid damage to health (resulting).

• Frei-Stuber, L.
• Utpatel, K.
• Hammer, S.
• Nowak, D.