RATIONALE: Asthma remission is a state of low to no disease activity. To date, little is known about predictors and the achievability of long-term asthma remission. OBJECTIVE: To identify clinical predictors and trends of long-term remission in a cohort of adults with mild to severe asthma. METHODS: This study included 203 adults with mild to severe asthma from the All Age Asthma Cohort, followed over 6 years. Participants attended 5 visits, during which type 2 inflammation markers (blood and sputum eosinophils, fractional exhaled nitric oxide), lung function measurements (oscillometry, spirometry), atopy and systemic comorbidities were assessed. Clinical remission was defined by an Asthma Control Test score of
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