The incidence of early recurrent venous thromboembolism: a systematic review and meta-analysis

BACKGROUND: Patients with venous thromboembolism (VTE) receive anticoagulation for at least 3 months. To evaluate recurrence risk thereafter, some strategies include D-dimer testing after discontinuing anticoagulation, which raises concern about early recurrence. OBJECTIVES: To assess the incidence of recurrent VTE within 30 days after stopping anticoagulation. METHODS: We conducted a systematic review of EMBASE, CENTRAL, and MEDLINE to identify controlled trials and cohort studies of adult noncancer patients with deep vein thrombosis of the leg and/or pulmonary embolism treated with anticoagulants for

• Eischer, L.
• Kyrle, P. A.
• Kaider, A.
• Schmidt, A.
• Wildner, B.
• Boc, A.
• Bradbury, C.
• Undas, A.
• Couturaud, F.
• Di Minno, M. N. D.
• Geersing, G. J.
• Jimenez, D.
• Parpia, S.
• Palareti, G.
• Poli, D.
• Potaczek, D. P.
• Prandoni, P.
• Schulman, S.
• van Hylckama Vlieg, A.
• Zabczyk, M.
• Eichinger, S.