INTRODUCTION: DACCORD is an ongoing, longitudinal, non-interventional study within the German COPD National Prospective Registry. This manuscript describes the baseline characteristics of the first 5924 participants, recruited between November 2012 and November 2013. METHODS: The main inclusion criteria are a physician diagnosis of COPD, age >/=40 years, and initiating or changing COPD maintenance medication. Data collected included: Demographic and disease characteristics; prescribed medication; symptoms; COPD Assessment Test (CAT); modified Medical Research Council dyspnoea score (mMRC); exacerbations; comorbidities; and forced expiratory volume in 1 s (FEV1). RESULTS: Approximately 60% of the population are male, with mean age of 65.7 years and FEV1 61.6% predicted. On entry to the study the majority of patients reported symptoms, most commonly exertional dyspnoea (85.9%) and cough (65.7%). According to GOLD 2010, 48.6% of patients were classified as GOLD II. GOLD 2011 classification was influenced by the symptoms criterion: 43.7 and 45.3% of patients were classified as GOLD B or D using CAT, compared with 26.4 and 34.0%, respectively, using mMRC. The majority of patients were receiving a LAMA-containing regimen, with 39.4% overall receiving ICS. A total of 78.3% of patients reported at least one comorbidity, most commonly cardiovascular. CONCLUSION: In conclusion, DACCORD is a large, prospective, non-interventional study that provides an informative and intriguing picture of the typical COPD patient in Germany.
- Worth, H.; Buhl, R.; Criee, C. P.; Kardos, P.; Mailander, C.; Vogelmeier, C.
Keywords
- Aged
- Comorbidity
- Female
- Forced Expiratory Volume
- Germany/epidemiology
- Humans
- Male
- Middle Aged
- Primary Health Care/methods/statistics & numerical data
- Prospective Studies
- Pulmonary Disease, Chronic Obstructive/diagnosis/*drug therapy/*epidemiology
- Registries
- Severity of Illness Index
- Spirometry/methods
- Treatment Outcome
- Baseline
- Copd
- Observational
- Registry