Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions

In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.

• Epp, A.
• Hobusch, J.
• Bartsch, Y. C.
• Petry, J.
• Lilienthal, G. M.
• Koeleman, C. A. M.
• Eschweiler, S.
• Mobs, C.
• Hall, A.
• Morris, S. C.
• Braumann, D.
• Engellenner, C.
• Bitterling, J.
• Rahmoller, J.
• Leliavski, A.
• Thurmann, R.
• Collin, M.
• Moremen, K. W.
• Strait, R. T.
• Blanchard, V.
• Petersen, A.
• Gemoll, T.
• Habermann, J. K.
• Petersen, F.
• Nandy, A.
• Kahlert, H.
• Hertl, M.
• Wuhrer, M.
• Pfutzner, W.
• Jappe, U.
• Finkelman, F. D.
• Ehlers, M.