BACKGROUND: The association between air pollution and rhinitis is not well established. AIM: The aim of this longitudinal analysis was to study the association between modeled air pollution at the subjects' home addresses and self-reported incidence of rhinitis. METHODS: We used data from 1533 adults from two multicentre cohorts' studies (EGEA and ECRHS). Rhinitis incidence was defined as reporting rhinitis at the second follow-up (2011 to 2013) but not at the first follow-up (2000 to 2007). Annual exposure to NO2, PM10 and PM2.5 at the participants' home addresses was estimated using land-use regression models developed by the ESCAPE project for the 2009-2010 period. Incidence rate ratios (IRR) were computed using Poisson regression. Pooled analysis, analyses by city and meta-regression testing for heterogeneity were carried out. RESULTS: No association between long-term air pollution exposure and incidence of rhinitis was found (adjusted IRR (aIRR) for an increase of 10mug.m(-3) of NO2: 1.00 [0.91-1.09], for an increase of 5mug.m(-3) of PM2.5: 0.88 [0.73-1.04]). Similar results were found in the two-pollutant model (aIRR for an increase of 10mug.m(-3) of NO2: 1.01 [0.87-1.17], for an increase of 5mug.m(-3) of PM2.5: 0.87 [0.68-1.08]). Results differed depending on the city, but no regional pattern emerged for any of the pollutants. CONCLUSIONS: This study did not find any consistent evidence of an association between long-term air pollution and incident rhinitis.
- Burte, E.
- Leynaert, B.
- Bono, R.
- Brunekreef, B.
- Bousquet, J.
- Carsin, A. E.
- De Hoogh, K.
- Forsberg, B.
- Gormand, F.
- Heinrich, J.
- Just, J.
- Marcon, A.
- Kunzli, N.
- Nieuwenhuijsen, M.
- Pin, I.
- Stempfelet, M.
- Sunyer, J.
- Villani, S.
- Siroux, V.
- Jarvis, D.
- Nadif, R.
- Jacquemin, B.
