Development of Trastuzumab-coupled, siRNA encapsulating mPolyplexes targeting HER2 overexpressing cancer cells

Over the past decades, significant advancements have been made in various medical fields; however, ovarian cancer (OC) remains inadequately addressed, predominantly relying on relatively toxic cytostatic treatments. In this study, we applied newly developed poly(

• Müller, J. T.
• Caruso, S.
• Nguyen, A.
• Jürgens, D. C.
• Kromer, A. P. E.
• Sheshachala, S.
• Adams, N. B. P.
• Merkel, O. M.