Science and Research

A Brief Report of Durvalumab With or Without Tremelimumab in Combination With Chemotherapy as First-Line Therapy for Metastatic Non-Small-Cell Lung Cancer: Outcomes by Tumor PD-L1 Expression in the Phase 3 POSEIDON Study

  • Garon, E. B.
  • Cho, B. C.
  • Luft, A.
  • Alatorre-Alexander, J.
  • Geater, S. L.
  • Trukhin, D.
  • Kim, S. W.
  • Ursol, G.
  • Hussein, M.
  • Lim, F. L.
  • Yang, C. T.
  • Araujo, L. H.
  • Saito, H.
  • Reinmuth, N.
  • Kohlmann, M.
  • Lowery, C.
  • Mann, H.
  • Peters, S.
  • Mok, T. S.
  • Johnson, M. L.

Keywords

  • Humans
  • *Carcinoma, Non-Small-Cell Lung/drug therapy/pathology
  • *Lung Neoplasms/drug therapy/pathology
  • *Antibodies, Monoclonal, Humanized/administration & dosage/therapeutic use
  • *Antineoplastic Combined Chemotherapy Protocols/therapeutic use
  • *Antibodies, Monoclonal/administration & dosage/therapeutic use
  • *B7-H1 Antigen/metabolism/antagonists & inhibitors
  • Male
  • Female
  • Treatment Outcome
  • Clinical trial
  • Cytotoxic T-lymphocyte-associated antigen 4
  • Immune checkpoint inhibitor
  • Immunotherapy
  • Programmed cell death ligand-1
Publication details
DOI: 10.1016/j.cllc.2024.03.003
Journal: Clin Lung Cancer
Pages: 266-273.e5 
Number: 3
Work Type: Original
Location: CPC-M
Disease Area: LC
Partner / Member: ASK
Access-Number: 38584069

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