Effectiveness of Single Versus Multiple Inhaler Triple Therapy on Mortality and Cardiopulmonary Risk Reduction in COPD: The SKOPOS-MAZI Study

BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) have elevated cardiopulmonary and mortality risk, particularly following exacerbations. While single inhaler triple therapies (SITTs), such as budesonide/glycopyrrolate/formoterol fumarate (BGF), reduce cardiopulmonary risk versus dual bronchodilator therapy, there is limited evidence comparing outcomes with SITTs versus multiple inhaler triple therapies (MITTs). METHODS: SKOPOS-MAZI was a retrospective comparative effectiveness study in patients with COPD aged

• Pollack, M.
• Rapsomaniki, E.
• Anzueto, A.
• Rhodes, K.
• Hawkins, N. M.
• Vogelmeier, C. F.
• Marshall, J.
• Müllerová, H.