There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5-30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1-2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run.
- Behrens, G. M. N.
- Cossmann, A.
- Stankov, M. V.
- Witte, T.
- Ernst, D.
- Happle, C.
- Jablonka, A.
Keywords
- Adolescent
- Adult
- Aged
- Antibodies, Viral/*blood
- Betacoronavirus
- Coronavirus Infections/diagnosis/*immunology
- Female
- Germany
- *Health Personnel
- Hospitals, University
- Humans
- Immunoglobulin A/blood
- Immunoglobulin G/blood
- Male
- Middle Aged
- Pandemics
- Pneumonia, Viral/diagnosis/*immunology
- Prevalence
- Seroepidemiologic Studies
- Serologic Tests
- Young Adult
- Covid-19
- Diagnostics
- Elisa
- Health-care professionals
- Health-care worker
- IgA
- IgG
- Immunoglobulin
- SARS-CoV-2
- Seroprevalence
