The detection of Mycobacterium tuberculosis complex DNA by PCR using formalin-fixed paraffin-embedded material has become an integral part of molecular-pathological diagnostics. We describe an approach that enables the detection of contamination by using Mycobacterium szulgai as a positive control, contributing to the reduction of false-positive results.
- Goldmann, T.
- Hillemann, D.
- Maurer, F.
- Kalsdorf, B.
- Krupar, R.
- Stellmacher, F.
- Perner, S.
Keywords
- DNA sequence analysis
- Molecular pathology
- Mycobacteria
- Polymerase chain reaction
- Quality control
