Science and Research

Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity

The identification of ubiquitous risk factors determining long-term morbidity is crucial in infants born prematurely when aiming to develop prevention strategies. In a cohort of deeply phenotyped infants born before 32 weeks gestational age, we successfully demonstrate that exposure to fine particulate matter during pregnancy is associated with increased odds of preeclampsia and altered birth weight percentiles, highlighting potential underlying effects on vascular and metabolic pathology in relation to the degree of immaturity.

  • Johansson, C.
  • Kraus, Y.
  • Sanchez, J. D. H.
  • Schubert, B.
  • Wolf, K.
  • Voss, C.
  • Stoeger, T.
  • Seegmuller, T.
  • Flemmer, A. W.
  • Forster, K.
  • Standl, M.
  • Hilgendorff, A.

Keywords

  • air pollution
  • birth weight
  • fine particulate matter
  • preeclampsia
  • preterm infant
Publication details
DOI: 10.1002/pul2.70320
Journal: Pulm Circ
Pages: e70320 
Work Type: Original
Location: BREATH, CPC-M
Disease Area: PALI
Partner / Member: HMGU, KUM, MHH
Access-Number: 42136984
See publication on PubMed


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