Science and Research

TIGOS: Randomized, Double-Blind, Multicenter Phase 3 Trial of BMS-986489 (BMS-986912 + Nivolumab FDC) in combination with Carboplatin plus Etoposide vs Atezolizumab in combination with Carboplatin plus Etoposide as First-line Therapy in Extensive-Stage Small Cell Lung Cancer (CA245-0001)

The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combina-tion) in Combination with Carboplatin plus Etoposide to that of Ate-zolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer.

Study details
Study-ID: NCT06646276, 2024-515740-23
Study-ID: NCT06646276, 2024-515740-23
DZL Disease Area: LC
DZL Disease Area: LC
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center, DZL on steering board
DZL Role: DZL recruiting center, DZL on steering board
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: ARCN, TLRC
DZL Participating Sites: ARCN, TLRC
Start Date: 25.02.2025
Completion Date: 05.09.2031
Status: Recruiting
Status: Recruiting
DZL recruiting center, DZL on steering board
Link to Study


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