Science and Research

rand. Phase III, double-blinded, multicenter study to evaluate safety/efficacy of neoadjuvant treatment with atezolizumab or placebo in combination with platinum-based chemo in patients with resectable stage IB−IIIA NSCLC

This is a randomized, double-blinded study designed to evaluate the efficacy, safety, pharmacokinetics, and immunogenicity of neoadjuvant treatment with atezolizumab (MPDL3280A) or placebo in combination with platinum-based chemotherapy in participants with resectable Stage II, IIIA, or select IIIB non-small cell lung cancer (NSCLC) followed by open-label adjuvant/postoperative atezolizumab or best supportive care and monitoring.

Study details
Study-ID: NCT03456063, 2017-002857-12
Study-ID: NCT03456063, 2017-002857-12
DZL Disease Area: LC
DZL Disease Area: LC
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL on steering board
DZL Role: DZL on steering board
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: ARCN
DZL Participating Sites: ARCN
Start Date: 24.04.2018
Completion Date: 31.12.2025
Status: Active / not recruiting
Status: Active / not recruiting
DZL on steering board
Link to Study


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