A multi-centre longitudinal study establishing a bio- and DNA bank for current and future research projects as well as establishing a registry with the essential clinical data of patients with cystic fibrosis for correlation with disease-modifying genes, new biomarkers and (new) cystic fibrosis pathogens for current and future research projects. Observational study, the registry should contain the essential clinical data of the patients (e.g. lung function findings, pathogen spectrum in the lungs, systemic inflammation) to enable the correlation of clinical parameters with disease-modifying genes, new CF pathogens, new biomarkers and CFTR function with and without therapeutic intervention. Establishment of a bio- and DNA bank for current and future research projects as well as establishment of a registry with the essential clinical data of patients with cystic fibrosis for correlation with disease-modifying genes, new biomarkers and (new) cystic fibrosis pathogens for current and future research projects.
