Science and Research

IMA401-101: A Phase Ia/Ib First-In-Human Clini-cal Trial to Evaluate the Safety, Tolerability and Initial Anti-tumor Activity of IMA401, a Bispecific T Cell Engaging Receptor Molecule (TCER®), in Patients With Recurrent and/or Refractory Solid Tumors.

The goal of this clinical trial is to evaluate the safety, tolerability and initial anti-tumor activity of IMA401 as monotherapy or in combina-tion with checkpoint inhibitor in patients with recurrent and/or refractory solid tumors. Patients' HLA status and expression of the MAGE-A4 and/or MAGE-A8 target in the tumor must be confirmed.

Study details
Study-ID: NCT05359445, 2023-506854-19-00
Study-ID: NCT05359445, 2023-506854-19-00
DZL Disease Area: LC
DZL Disease Area: LC
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center
DZL Role: DZL recruiting center
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: TLRC
DZL Participating Sites: TLRC
Start Date: 19.05.2022
Completion Date: 31.12.2029
Status: Recruiting
Status: Recruiting
DZL recruiting center
Link to Study


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