Science and Research

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023) (HARMONIZE)

Researchers are looking for new ways to treat people with a type of pulmonary hypertension called combined postcapillary and precapillary pulmonary hypertension (Cpc-PH). This study focuses on Cpc-PH that is caused by heart failure with preserved ejection fraction (HFpEF). Researchers want to know if the study treatment, sotatercept, can treat people with Cpc-PH caused by HFpEF. This is an extension study, which means people who took part in a certain study on sotatercept for Cpc-PH (called a parent study) may be able to join this study. In this extension study, people will take sotatercept and researchers will follow their health for a longer time. The main goal of this extension study is to learn about the long-term safety of sotatercept and if people tolerate it over a longer period of time.

Study details
Study-ID: NCT06814145, 2024-515773-99
Study-ID: NCT06814145, 2024-515773-99
DZL Disease Area: PH
DZL Disease Area: PH
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center
DZL Role: DZL recruiting center
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: TLRC, BREATH, UGMLC
DZL Participating Sites: TLRC, BREATH, UGMLC
Start Date: 16.04.2025
Completion Date: 30.03.2029
Status: Recruiting
Status: Recruiting
DZL recruiting center
Link to Study


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