The primary goal of the study was to assess the efficacy and safety of minimally-invasive ECCO2R using RRT platforms in combination with RRT or as a “standalone” procedure as well as enhancing or maintaining lung-protective ventilation. Clinical, laboratory, and ventilation parameters were assessed at different time points up to 48 h after initiation of minimally-invasive ECCO2R. Clinical scores, such as SOFA, APACHE 2 (Acute Physiology And Chronic Health Evaluation 2) II and SAPS (Simplified Acute Physiology Score) II were additionally analyzed.
