Science and Research

A Phase III, Randomized, double-blinded, placebo-controlled study of Tiragolumab, an Anti-Tigit Antibody, in combination with Atezolizumab compared with Placebo in Combination with Atezolizumab in Patients with Previously untreated locally advanced unrese

The purpose of the study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab in participants with previously untreated locally advanced, unresectable or metastatic PD-L1-selected non-small cell lung cancer (NSCLC), with no epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase (ALK) translocation. Eligible participants will be randomized in a 1:1 ratio to receive either tiragolumab plus atezolizumab or placebo plus atezolizumab.

Study details
Study-ID: NCT04294810, 2019-002925-31
Study-ID: NCT04294810, 2019-002925-31
DZL Disease Area: LC
DZL Disease Area: LC
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center
DZL Role: DZL recruiting center
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: ARCN
DZL Participating Sites: ARCN
Start Date: 04.03.2020
Completion Date: 31.01.2026
Status: Active / not recruiting
Status: Active / not recruiting
DZL recruiting center
Link to Study


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