Science and Research

A Phase III, open label, ramdomized study to investigate the efficacy and safety of MPDL3280A compared with best supportive care following adjuvant Cisplatin-based Chemoth. In PDL-1 selected pat. With compl. Resected Stage IB-IIIA NSCLC

This is a Phase III, global, multicenter, open-label, randomized study to compare the efficacy and safety of 16 cycles (1 cycle duration=21 days) of atezolizumab (MPDL3280A) treatment compared with best supportive care (BSC) in participants with Stage IB-Stage IIIA non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy, as measured by disease-free survival (DFS) as assessed by the investigator and overall survival (OS). Participants, after completing up to 4 cycles of adjuvant cisplatin-based chemotherapy, will be randomized in a 1:1 ratio to receive atezolizumab for 16 cycles or BSC.

Study details
Study-ID: NCT02486718, 2014-003205-15
Study-ID: NCT02486718, 2014-003205-15
DZL Disease Area: LC
DZL Disease Area: LC
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL on steering board
DZL Role: DZL on steering board
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: ARCN
DZL Participating Sites: ARCN
Start Date: 31.10.2015
Completion Date: 30.08.2035
Status: Active / not recruiting
Status: Active / not recruiting
DZL on steering board
Link to Study


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