Science and Research

A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Who Are Homozygous or Heterozygous for the F508del Mutation (VX17-659-105)

This study will evaluate the long-term safety and tolerability of VX-659 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous or heterozygous for the F508del mutation.

Study details
Study-ID: NCT03447262, 2017-004134-29
Study-ID: NCT03447262, 2017-004134-29
DZL Disease Area: CFBE
DZL Disease Area: CFBE
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center
DZL Role: DZL recruiting center
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: ARCN, BIH / Charité - Associated Partner, BREATH, CPC-M
DZL Participating Sites: ARCN, BIH / Charité - Associated Partner, BREATH, CPC-M
Start Date: 13.11.2018
Completion Date: 04.02.2021
Status: Terminated
Status: Terminated
DZL recruiting center
Link to Study


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