Science and Research

A phase 3 Double-blind, Randomized, Placebo-controlled Study Evaluation the Efficacy and Safety of ELX/TEZ/IVA in Cystic Fibrosis Subjects 6 Years of Age and older with a Non-F508del ELX/TEZ/IVA-responsive CFTR Mutation

This study evaluated the efficacy, pharmacodynamics (PD) and safe-ty of ELX/TEZ/IVA in participants 6 years of age and older with a non-F508del ELX/TEZ/IVA-responsive cystic fibrosis transmembrane conductance regulator gene (CFTR) mutation.

Study details
Study-ID: NCT05274269, 2021-005320-38
Study-ID: NCT05274269, 2021-005320-38
DZL Disease Area: CFBE
DZL Disease Area: CFBE
Study Type: Interventional
Study Type: Interventional
DZL Role: DZL recruiting center, DZL on steering board
DZL Role: DZL recruiting center, DZL on steering board
Funding: Externally - industry
Funding: Externally - industry
DZL Participating Sites: BIH / Charité - Associated Partner, BREATH, CPC-M, UGMLC
DZL Participating Sites: BIH / Charité - Associated Partner, BREATH, CPC-M, UGMLC
Start Date: 01.05.2022
Completion Date: 06.10.2023
Status: Closed
Status: Closed
DZL recruiting center, DZL on steering board
Link to Study


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