The bone marrow (BM) hematopoietic system (HS) gives rise to blood cells originating from hematopoietic stem cells (HSCs), including megakaryocytes (MKs) and red blood cells (erythrocytes; RBCs). Many steps of the cell-fate decision remain to be elucidated, being important for cancer treatment. To explore the role of Wnt/
- Yalcin, B. H.
- Macas, J.
- Wiercinska, E.
- Harter, P. N.
- Fawaz, M.
- Schmachtel, T.
- Ghiro, I.
- Bieniek, E.
- Kosanovic, D.
- Thom, S.
- Fruttiger, M.
- Taketo, M. M.
- Schermuly, R. T.
- Rieger, M. A.
- Plate, K. H.
- Bonig, H.
- Liebner, S.
Keywords
- Animals
- Mice
- *beta Catenin/metabolism
- Megakaryocyte-Erythroid Progenitor Cells
- *Megakaryocytes/metabolism
- Proto-Oncogene Proteins c-sis/metabolism
- *Thrombopoiesis/physiology
- Wnt signaling
- cell-fate decision
- erythrocytes
- maegakaryopoiesis
- megakaryocytes
- β-catenin
