Science and Research

Neutrophils negatively control IL-17A-producing

BACKGROUND: In addition to serving as the primary effector cells against infections, neutrophils have been implicated in the regulation of both innate and adaptive immunity. In this study, we aimed to investigate the role of neutrophils in the regulation of the immune system under physiological conditions. METHODS: The in vivo effect of neutrophils on the immune system was examined using neutropenic mice. The interaction between neutrophils and

  • Yu, X.
  • Yue, X.
  • Tchudjin Magatsin, J. D.
  • Marwitz, S.
  • Behrends, J.
  • Goldmann, T.
  • Opferman, J. T.
  • Kasper, B.
  • Petersen, F.

Keywords

  • Animals
  • *Interleukin-17/immunology/metabolism
  • *Neutrophils/immunology/metabolism
  • Mice
  • *Receptors, Antigen, T-Cell, gamma-delta/metabolism/immunology
  • *Cell Communication/immunology
  • Mice, Inbred C57BL
  • Coculture Techniques
  • *Intraepithelial Lymphocytes/immunology
  • Il-17a
  • cell death
  • innate immunity
  • neutrophils
  • physiological condition
  • γδ T cells
Publication details
DOI: 10.3389/fimmu.2025.1542191
Journal: Front Immunol
Pages: 1542191 
Work Type: Original
Location: ARCN
Disease Area: AA
Partner / Member: FZB
Access-Number: 40181985

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