Science and Research

Imaging Inflammation - From Whole Body Imaging to Cellular Resolution

Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging modalities and evaluated the recent findings on preclinical and clinical inflammation imaging. The focus has been on the feasibility of imaging to aid in inflammation precision medicine, and the key challenges and opportunities of the imaging modalities are presented. Some examples of the current usage in clinics/close to clinics have been brought out as an example. This review evaluates the future prospects of the imaging technologies for clinical applications in precision medicine from the pre-clinical development point of view.

  • Peñate Medina, T.
  • Kolb, J. P.
  • Hüttmann, G.
  • Huber, R.
  • Peñate Medina, O.
  • Ha, L.
  • Ulloa, P.
  • Larsen, N.
  • Ferrari, A.
  • Rafecas, M.
  • Ellrichmann, M.
  • Pravdivtseva, M. S.
  • Anikeeva, M.
  • Humbert, J.
  • Both, M.
  • Hundt, J. E.
  • Hövener, J. B.

Keywords

  • Mri
  • Optical coherence tomography (OCT)
  • Pet
  • Spect
  • Two-Photon microscopy (TPM)
  • hyperpolarization
  • optical imaging
  • precision medicine
  • or financial relationships that could be construed as a potential conflict of
  • interest.
Publication details
DOI: 10.3389/fimmu.2021.692222
Journal: Front Immunol
Pages: 692222 
Work Type: Review
Location: Assoziierter Partner, ARCN
Disease Area: PLI
Partner / Member: CAU, UKSH (Lübeck)
Access-Number: 34248987

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