Science and Research

Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with (213)Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors

Radiopharmaceutical therapies (RPTs) based on fibroblast activation protein (FAP) and FAP inhibitors (FAPIs) are a new option for progressive metastatic cancer in patients pretreated multiple times. To date, published in-human data refer to initial experiences with

  • Helisch, A.
  • Kratochwil, C.
  • Kleist, C.
  • Krämer, S.
  • Rosales Castillo, J. J.
  • Dendl, K.
  • Rathke, H.
  • von Goetze, I.
  • Schreckenberger, M.
  • Jäger, D.
  • Lindner, T.
  • Mier, W.
  • Giesel, F.
  • Haberkorn, U.
  • Röhrich, M.

Keywords

  • Fapi
  • bismuth
  • radiopharmaceutical therapy
  • targeted therapy
  • α-therapy
Publication details
DOI: 10.2967/jnumed.124.268386
Journal: J Nucl Med
Work Type: Original
Location: TLRC
Disease Area: LC
Partner / Member: UKHD
Access-Number: 39477492

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