Science and Research

Simple approach for aberration-corrected OCT imaging of the human retina

Aberration-corrected imaging of human photoreceptor cells, whether hardware or software based, presently requires a complex and expensive setup. Here we use a simple and inexpensive off-axis full-field time-domain optical coherence tomography (OCT) approach to acquire volumetric data of an in vivo human retina. Full volumetric data are recorded in 1.3 s. After computationally correcting for aberrations, single photoreceptor cells were visualized. In addition, the numerical correction of ametropia is demonstrated. Our implementation of full-field optical coherence tomography combines a low technical complexity with the possibility for computational image correction.

  • Sudkamp, H.
  • Hillmann, D.
  • Koch, P.
  • Endt, M. V.
  • Spahr, H.
  • Munst, M.
  • Pfaffle, C.
  • Birngruber, R.
  • Huttmann, G.

Keywords

  • Algorithms
  • Costs and Cost Analysis
  • Humans
  • *Image Processing, Computer-Assisted
  • Retina/*diagnostic imaging
  • Time Factors
  • Tomography, Optical Coherence/economics/*methods
Publication details
DOI: 10.1364/OL.43.004224
Journal: Optics letters
Pages: 4224-4227 
Number: 17
Work Type: Original
Location: ARCN
Disease Area: PLI
Partner / Member: UZL
Access-Number: 30160757
See publication on PubMed

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