Science and Research

In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.

  • Sudkamp, H.
  • Koch, P.
  • Spahr, H.
  • Hillmann, D.
  • Franke, G.
  • Munst, M.
  • Reinholz, F.
  • Birngruber, R.
  • Huttmann, G.
Publication details
DOI: 10.1364/OL.41.004987
Journal: Optics letters
Pages: 4987-4990 
Number: 21
Work Type: Original
Location: ARCN
Disease Area: PLI
Partner / Member: UzL
Access-Number: 27805666
See publication on PubMed

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