A Long-Term Follow-Up Study of Sotatercept for Treatment of Pulmonary Arterial Hypertension: Interim Results of SOTERIA

BACKGROUND: SOTERIA (NCT04796337) is an ongoing open-label study evaluating long-term safety, tolerability, and efficacy of sotatercept in participants with pulmonary arterial hypertension (PAH). METHODS: Eligible adults with PAH on stable background therapy who completed a prior sotatercept study without early discontinuation were enrolled. Participants received subcutaneous sotatercept (

• Preston, I. R.
• Badesch, D.
• Ghofrani, H. A.
• Gibbs, J. S. R.
• Gomberg-Maitland, M.
• Hoeper, M. M.
• Humbert, M.
• McLaughlin, V. V.
• Waxman, A. B.
• Manimaran, S.
• Mikhailova, E.
• Reddy, M.
• Lau, A.
• de Oliveira Pena, J.
• Souza, R.